Profhilo treatment: how it works, results, prices & comparing clinics in your area

23 February 2026

Many people notice that over the years their skin becomes less firm, less radiant, and drier. Fine lines appear, the skin loses elasticity, and the face can look more tired than they feel. This process is largely caused by a decrease in collagen, elastin, and hyaluronic acid in the skin.

Profhilo is an innovative injectable specifically designed to hydrate and improve the skin from within. Unlike traditional fillers, Profhilo does not add volume, but instead stimulates the skin to regenerate itself.

Because technique, experience, and treatment approach can vary significantly from one doctor to another, comparing clinics in your area is important. This helps you understand differences in approach, expected results, and safety.

Profhilo treatment: how it works, results, prices & comparing clinics in your area

This is what you need to know about Profhilo

Profhilo deeply hydrates the skin from within.

  • It stimulates collagen and elastin production.

  • Results become gradually visible over several weeks.

  • The treatment takes approximately 15 to 30 minutes.

  • The effects last about 6 to 9 months.

  • Natural skin improvement is the main focus.

  • Comparing clinics in your area helps you choose an experienced doctor.

Why results and experiences with Profhilo can differ

Why does the result of Profhilo look different for everyone?

The result of Profhilo varies per person due to differences in skin structure, age, collagen density, and hydration levels. Profhilo contains hyaluronic acid that spreads evenly within the skin and stimulates fibroblasts to produce collagen and elastin. When the baseline condition of the skin differs, the tissue responds differently to this biostimulation. In thinner or significantly lax skin, the effect may be more subtle, while firmer skin may show visible improvement in elasticity and hydration more quickly. As a result, both the degree and speed of visible improvement vary per individual.

Why does one person see results sooner after a Profhilo treatment than another?

The timing of visible results differs due to variations in skin condition, age, and metabolism. Profhilo distributes hyaluronic acid within the skin and stimulates fibroblasts to produce collagen and elastin. When cellular activity and circulation are higher, this biostimulation occurs more quickly, leading to earlier visible skin improvement. With slower metabolism or reduced collagen production, the process takes longer, and results appear later. Therefore, the speed of visible tightening and hydration differs from person to person.

Why are two Profhilo treatments sometimes needed?

Two Profhilo treatments are often required because collagen production is a gradual biological process. The injected hyaluronic acid spreads through the skin and stimulates fibroblasts to produce new collagen and elastin. One treatment initiates this process, but a second session enhances and prolongs the effect by reactivating cellular activity. In cases of reduced skin elasticity or lower collagen density, additional stimulation is necessary to achieve noticeable improvement. As a result, outcomes are typically more stable and visible after a second session.

Why do Profhilo prices vary between clinics?

Profhilo prices differ due to variations in purchasing costs, staffing expenses, and practitioner experience. These factors determine the total treatment cost, including the product, consultation time, and medical responsibility. Clinics with higher overhead or specialized doctors often charge higher fees to cover these costs. Location and clinic structure also influence operating expenses. This leads to price differences between clinics for the same treatment.

Why is comparing clinics important for a Profhilo treatment?

Comparing clinics in your area is important because providers differ in medical expertise, treatment protocols, and pricing structure. These differences influence how the product is injected and how potential complications are assessed and managed. The experience of the practitioner and adherence to medical guidelines affect both safety and consistency of results. Consultation length and aftercare may also vary, influencing overall quality of care. Therefore, comparing clinics helps you understand factors that impact treatment outcomes and risk profile.

What is Profhilo & how does it work?

Profhilo in short

  • Type of treatment: Injectable skinbooster

  • Goal: Hydration and skin rejuvenation

  • Visible results: Yes

  • Average duration: 15–30 minutes

  • Key success factor: Technique and experience of the doctor

What exactly does Profhilo do?

Profhilo consists of pure hyaluronic acid with a unique formulation that spreads evenly beneath the skin. It deeply hydrates and stimulates skin regeneration.

How does the Profhilo treatment work?

  • Preparation: Skin analysis and discussion of goals

  • Treatment: Injections at fixed BAP points

  • Immediately after: Mild swelling may occur, which usually subsides quickly

Is Profhilo a filler?

No, Profhilo is not a volumizing product but a skin-enhancing treatment.

What can go wrong with a Profhilo treatment?

With a Profhilo treatment, mild side effects may occur, such as temporary swelling, redness, and small bumps at the injection sites. These usually disappear within 24 to 48 hours. Serious complications are rare, especially when the treatment is performed by an experienced doctor with knowledge of proper injection technique and anatomy.

What are the most common side effects of Profhilo?

The most common side effects are mild swelling, redness, tenderness, and small bumps at the injection points. This is a normal skin reaction to the product and the injections. In most cases, these symptoms resolve on their own within one to two days.

Can Profhilo feel lumpy?

Shortly after treatment, small bumps may be felt under the skin. This happens because the product temporarily remains at the injection points before gradually spreading. These bumps dissolve on their own and are usually no longer visible or noticeable within a few days.

Is Profhilo safe in the long term?

Profhilo consists of pure hyaluronic acid, a substance naturally found in the body. The product has been extensively clinically tested and is widely used in aesthetic medicine worldwide. When used correctly by a qualified doctor, Profhilo is considered a safe long-term treatment.

When should you contact a doctor after a Profhilo treatment?

It is advisable to contact a doctor if swelling persists, if you experience severe pain, redness that does not decrease, or noticeable asymmetry lasting more than a few days. Although this is rare, it is important to seek professional advice if you have concerns.

Can the results of Profhilo be corrected?

Because Profhilo spreads evenly through the skin and is not a volumizing filler, minor irregularities are usually corrected naturally by the body. In exceptional cases, a doctor may recommend additional treatment, but in most situations, the result settles naturally over time.

Popular Profhilo treatments by area

  • Face: Improved skin texture

  • Neck: Firmer skin around the neck/under-chin area

  • Décolleté: Hydration and radiance

  • Hands: Fewer lines, increased elasticity

Profhilo: results, duration & safety

Profhilo provides:

  • Smoother skin

  • Increased elasticity

  • A fresher appearance

Average duration: 6 to 9 months

Safety depends on:

  • The experience of the doctor

  • Proper injection technique

  • Hygiene

Profhilo before and after photos

Profhilo picture of Moerman Clinic (before)
Profhilo picture of Moerman Clinic (after)
These pictures are from Moerman Clinic
Profhilo picture of Beautifier Maastricht (before)
Profhilo picture of Beautifier Maastricht (after)
These pictures are from Beautifier Maastricht
Profhilo picture of SW Clinic (before)
Profhilo picture of SW Clinic (after)
These pictures are from SW Clinic
Profhilo picture of Huidkliniek Twente (before)
Profhilo picture of Huidkliniek Twente (after)
These pictures are from Huidkliniek Twente
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of SkinSurgery Clinics Den Haag (before)
Profhilo picture of SkinSurgery Clinics Den Haag (after)
These pictures are from SkinSurgery Clinics Den Haag
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Dokter Lylian Logtenberg Kliniek (before)
Profhilo picture of Dokter Lylian Logtenberg Kliniek (after)
These pictures are from Dokter Lylian Logtenberg Kliniek
Profhilo picture of Dikrama Clinics (before)
Profhilo picture of Dikrama Clinics (after)
These pictures are from Dikrama Clinics

How long does Profhilo last & safety

Effects can remain visible for up to 6–9 months. For longer-lasting results, two treatments spaced 4–6 weeks apart are often recommended. Aftercare and proper skincare help maintain more durable results. Side effects are usually mild and short-lived.

Profhilo: who is it suitable / less suitable for

Suitable if:

  • You want a natural skin improvement

  • Your skin lacks hydration and elasticity

  • You do not want an intensive procedure

Less suitable if:

  • You are looking for immediate volume enhancement

  • You are pregnant or have certain skin conditions

  • You have an infection in the treatment area

How do you determine if Profhilo is right for you?

  1. 1 What is your goal: hydration or volume?
  2. 2 Do you have dynamic or static signs of aging?
  3. 3 Which areas require an experienced doctor?
  4. 4 Do you want temporary results or periodic maintenance?
  5. 5 Which doctor has experience with Profhilo?

Profhilo: prices, experiences & comparison

Profhilo prices vary by clinic, treatment area, and the experience of the doctor. Compare prices in your area to get a good sense of market value.

TreatmentUnitCity/countryPrice
Profhilo treatmentper 2 ml United Kingdom £ 50Lowest price
Profhilo treatmentper 2 ml United Kingdom £ 258Average price
Profhilo treatmentper 2 ml United Kingdom £ 800Highest price

Compare prices in your area

Compare on experience & price Make an appointment immediately

Profhilo experiences: what do people really pay attention to?

People mainly focus on a natural-looking result, clarity during the consultation, trust in the doctor, and transparency about risks. Context is more important than star ratings alone.

Profhilo compared with alternatives

Profhilo vs fillers:

Profhilo improves skin quality; fillers add volume.

Profhilo vs Botox:

Botox relaxes muscles, Profhilo hydrates and stimulates.

Reviews Profhilo

I was recommend by a friend to visit Aldo in London and have a consultation with him and have an opinion what would be ideal for me. We planned to proceed with profhilo and profhilo structura I knew the product but I didn’t know someone can inject in such a way that I didn’t feel anything Also my face looks so natural and so hydrated and lifted I can’t recom... Show more »
I was recommend by a friend to visit Aldo in London and have a consultation with him and have an opinion what would be ideal for me.
We planned to proceed with profhilo and profhilo structura I knew the product but I didn’t know someone can inject in such a way that I didn’t feel anything
Also my face looks so natural and so hydrated and lifted
I can’t recommend him enough !
Definetly will visit Aldo again. Show less »
Elena Teodora
goaesthetix
14 February 2026 12:12
“I visited Nuvo Aesthetics with concerns about ageing and had such a thorough, reassuring consultation with Nurse Lauren. She recommended Profhilo Structura and I honestly couldn’t be happier with the results. I felt listened to, well cared for, and in very safe hands. Highly recommend!”
Shelley Thompson
NuVo Aesthetics
14 February 2026 11:11
I’ve been to 53 Aesthetics three times now, for one Botox appointment and two Profhilo sessions. I have booked Dr Shiv for all three appointments and highly recommend, she is very professional and knowledgeable, whilst also super friendly and makes you feel at ease throughout. My skin typically bruises very easily so she has gone above and beyond to adapt to... Show more »
I’ve been to 53 Aesthetics three times now, for one Botox appointment and two Profhilo sessions. I have booked Dr Shiv for all three appointments and highly recommend, she is very professional and knowledgeable, whilst also super friendly and makes you feel at ease throughout. My skin typically bruises very easily so she has gone above and beyond to adapt to my skin’s needs. The salon staff are all very friendly too and it feels like a clean and calm environment. Thank you Dr Shiv! 😊 Show less »
30 January 2026 16:04
I came to Clare for hair removal, dermal filler and profhilo. I’ve come to the end of my sessions for hair removal and I wish I started sooner! Can’t wait for my next profhilo skin booster-highly recommend.
Victoria Jupp
Skinsense Clinic
30 January 2026 10:10
I can’t recommend Dr Edwards highly enough. From the very first point of contact with Siobhan, I was impressed by the personable, professional and caring approach. The open and honest discussion about treatment options from the extremely experienced Dr Edwards helped me decide to have some Botox and Profhilo treatments with this SafeFace accredited clinician... Show more »
I can’t recommend Dr Edwards highly enough. From the very first point of contact with Siobhan, I was impressed by the personable, professional and caring approach. The open and honest discussion about treatment options from the extremely experienced Dr Edwards helped me decide to have some Botox and Profhilo treatments with this SafeFace accredited clinician. Both Dr Edwards and Siobhan’s calm personas made for a relaxing environment which helped mitigate any anxiety I was feeling. I felt reassured and knew I was in safe hands and can’t recommend you enough. The results are fantastic and I’m so pleased with them. I will absolutely be returning to see you both in the near future. Thank you so much to the both of you. Show less »
Jennifer Allen
Dr Edwards Aesthetics
22 January 2026 22:10

Profhilo doctors & clinics comparison

A doctor’s expertise makes the difference in results, safety, and aftercare. Compare clinics in your area based on experience, treatment approach, and honest advice.

Cosmetic specialists in United Kingdom

Lindsay Bridge
Lindsay Bridge
Profession
-
Botox zone from
-
Filler per ml from
£ 250,00
View this specialist
Kerri-Lee Clark
Dr. Kerri-Lee Clark
Profession
Dentist
Botox zone from
£ 195,00
Filler per ml from
£ 275,00
View this specialist
Austin Brewer
Austin Brewer
Profession
Advanced Nurse Practitioner
Botox zone from
-
Filler per ml from
-
View this specialist
Amber Halliday
Dr. Amber Halliday
Profession
Aesthetic Doctor
Botox zone from
£ 185,00
Filler per ml from
£ 235,00
View this specialist
Rick Howard-Pay
Rick Howard-Pay
Profession
-
Botox zone from
£ 109,00
Filler per ml from
£ 149,00
View this specialist
Muqaddas Shafiq
Dr. Muqaddas Shafiq
Profession
Aesthetic Doctor
Botox zone from
£ 175,00
Filler per ml from
£ 275,00
View this specialist
Mandie Dransfield
Dr. Mandie Dransfield
Profession
Nurse prescriber (V300 Independent)
Botox zone from
-
Filler per ml from
-
View this specialist

Differences between clinics for Profhilo treatments

  • Consultation approach: Medical history and risk management

  • Price transparency: Clear pricing

  • Aftercare: Availability after treatment

Compare clinics in United Kingdom

Promoted
Now being
viewed
Hampstead Aesthetics
Hampstead Aesthetics
London, West End Lane 269
Botox zone from
£ 180,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 300,00
View profile
Promoted
Now being
viewed
Lindsay Owens Aesthetics
Lindsay Owens Aesthetics
Sevenoaks, Plaxdale Green Road
Botox zone from
-
Filler per ml from
£ 250,00
Profhilo per 2 ml from
-
View profile
Promoted
Now being
viewed
Laser Clinics UK - Plymouth
Laser Clinics UK - Plymouth
Plymouth, Charles Street 1
Botox zone from
£ 135,00
Filler per ml from
£ 199,00
Profhilo per 2 ml from
£ 325,00
View profile
Promoted
Now being
viewed
Thérapie Clinic - Liverpool
Thérapie Clinic - Liverpool
Liverpool, South John Street 46a
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile
Promoted
Now being
viewed
Laser Clinics UK - Manchester
Laser Clinics UK - Manchester
Manchester
Botox zone from
£ 135,00
Filler per ml from
£ 199,00
Profhilo per 2 ml from
£ 325,00
View profile
Promoted
Now being
viewed
Thérapie Clinic - Marylebone
Thérapie Clinic - Marylebone
London, Wigmore Street
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile
Promoted
Now being
viewed
Thérapie Clinic - Bath
Thérapie Clinic - Bath
Bath, Southgate Place 12
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile
Promoted
Now being
viewed
Thérapie Clinic - Belfast
Thérapie Clinic - Belfast
Belfast, Ann Street 36
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile

Frequently asked questions about Profhilo

How long does Profhilo last?

What are the disadvantages of Profhilo?

What does Profhilo do to your face?

What should you not do after Profhilo?

What are the best fillers?

Can Profhilo be combined?

Profhilo is an effective and relatively gentle treatment for skin improvement and hydration with natural-looking results. Results vary per person and strongly depend on the expertise of the doctor. Compare doctors and clinics in your area to make the right choice. This information does not replace a personal consultation.

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