Profhilo treatment: how it works, results, prices & comparing clinics in your area

22 February 2026

Many people notice that over the years their skin becomes less firm, less radiant, and drier. Fine lines appear, the skin loses elasticity, and the face can look more tired than they feel. This process is largely caused by a decrease in collagen, elastin, and hyaluronic acid in the skin.

Profhilo is an innovative injectable specifically designed to hydrate and improve the skin from within. Unlike traditional fillers, Profhilo does not add volume, but instead stimulates the skin to regenerate itself.

Because technique, experience, and treatment approach can vary significantly from one doctor to another, comparing clinics in your area is important. This helps you understand differences in approach, expected results, and safety.

Profhilo treatment: how it works, results, prices & comparing clinics in your area

This is what you need to know about Profhilo

Profhilo deeply hydrates the skin from within.

  • It stimulates collagen and elastin production.

  • Results become gradually visible over several weeks.

  • The treatment takes approximately 15 to 30 minutes.

  • The effects last about 6 to 9 months.

  • Natural skin improvement is the main focus.

  • Comparing clinics in your area helps you choose an experienced doctor.

Why results and experiences with Profhilo can differ

Why does the result of Profhilo look different for everyone?

The result of Profhilo varies per person due to differences in skin structure, age, collagen density, and hydration levels. Profhilo contains hyaluronic acid that spreads evenly within the skin and stimulates fibroblasts to produce collagen and elastin. When the baseline condition of the skin differs, the tissue responds differently to this biostimulation. In thinner or significantly lax skin, the effect may be more subtle, while firmer skin may show visible improvement in elasticity and hydration more quickly. As a result, both the degree and speed of visible improvement vary per individual.

Why does one person see results sooner after a Profhilo treatment than another?

The timing of visible results differs due to variations in skin condition, age, and metabolism. Profhilo distributes hyaluronic acid within the skin and stimulates fibroblasts to produce collagen and elastin. When cellular activity and circulation are higher, this biostimulation occurs more quickly, leading to earlier visible skin improvement. With slower metabolism or reduced collagen production, the process takes longer, and results appear later. Therefore, the speed of visible tightening and hydration differs from person to person.

Why are two Profhilo treatments sometimes needed?

Two Profhilo treatments are often required because collagen production is a gradual biological process. The injected hyaluronic acid spreads through the skin and stimulates fibroblasts to produce new collagen and elastin. One treatment initiates this process, but a second session enhances and prolongs the effect by reactivating cellular activity. In cases of reduced skin elasticity or lower collagen density, additional stimulation is necessary to achieve noticeable improvement. As a result, outcomes are typically more stable and visible after a second session.

Why do Profhilo prices vary between clinics?

Profhilo prices differ due to variations in purchasing costs, staffing expenses, and practitioner experience. These factors determine the total treatment cost, including the product, consultation time, and medical responsibility. Clinics with higher overhead or specialized doctors often charge higher fees to cover these costs. Location and clinic structure also influence operating expenses. This leads to price differences between clinics for the same treatment.

Why is comparing clinics important for a Profhilo treatment?

Comparing clinics in your area is important because providers differ in medical expertise, treatment protocols, and pricing structure. These differences influence how the product is injected and how potential complications are assessed and managed. The experience of the practitioner and adherence to medical guidelines affect both safety and consistency of results. Consultation length and aftercare may also vary, influencing overall quality of care. Therefore, comparing clinics helps you understand factors that impact treatment outcomes and risk profile.

What is Profhilo & how does it work?

Profhilo in short

  • Type of treatment: Injectable skinbooster

  • Goal: Hydration and skin rejuvenation

  • Visible results: Yes

  • Average duration: 15–30 minutes

  • Key success factor: Technique and experience of the doctor

What exactly does Profhilo do?

Profhilo consists of pure hyaluronic acid with a unique formulation that spreads evenly beneath the skin. It deeply hydrates and stimulates skin regeneration.

How does the Profhilo treatment work?

  • Preparation: Skin analysis and discussion of goals

  • Treatment: Injections at fixed BAP points

  • Immediately after: Mild swelling may occur, which usually subsides quickly

Is Profhilo a filler?

No, Profhilo is not a volumizing product but a skin-enhancing treatment.

What can go wrong with a Profhilo treatment?

With a Profhilo treatment, mild side effects may occur, such as temporary swelling, redness, and small bumps at the injection sites. These usually disappear within 24 to 48 hours. Serious complications are rare, especially when the treatment is performed by an experienced doctor with knowledge of proper injection technique and anatomy.

What are the most common side effects of Profhilo?

The most common side effects are mild swelling, redness, tenderness, and small bumps at the injection points. This is a normal skin reaction to the product and the injections. In most cases, these symptoms resolve on their own within one to two days.

Can Profhilo feel lumpy?

Shortly after treatment, small bumps may be felt under the skin. This happens because the product temporarily remains at the injection points before gradually spreading. These bumps dissolve on their own and are usually no longer visible or noticeable within a few days.

Is Profhilo safe in the long term?

Profhilo consists of pure hyaluronic acid, a substance naturally found in the body. The product has been extensively clinically tested and is widely used in aesthetic medicine worldwide. When used correctly by a qualified doctor, Profhilo is considered a safe long-term treatment.

When should you contact a doctor after a Profhilo treatment?

It is advisable to contact a doctor if swelling persists, if you experience severe pain, redness that does not decrease, or noticeable asymmetry lasting more than a few days. Although this is rare, it is important to seek professional advice if you have concerns.

Can the results of Profhilo be corrected?

Because Profhilo spreads evenly through the skin and is not a volumizing filler, minor irregularities are usually corrected naturally by the body. In exceptional cases, a doctor may recommend additional treatment, but in most situations, the result settles naturally over time.

Popular Profhilo treatments by area

  • Face: Improved skin texture

  • Neck: Firmer skin around the neck/under-chin area

  • Décolleté: Hydration and radiance

  • Hands: Fewer lines, increased elasticity

Profhilo: results, duration & safety

Profhilo provides:

  • Smoother skin

  • Increased elasticity

  • A fresher appearance

Average duration: 6 to 9 months

Safety depends on:

  • The experience of the doctor

  • Proper injection technique

  • Hygiene

Profhilo before and after photos

Profhilo picture of Dikrama Clinics (before)
Profhilo picture of Dikrama Clinics (after)
These pictures are from Dikrama Clinics
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Dokter Lylian Logtenberg Kliniek (before)
Profhilo picture of Dokter Lylian Logtenberg Kliniek (after)
These pictures are from Dokter Lylian Logtenberg Kliniek
Profhilo picture of Beautifier Maastricht (before)
Profhilo picture of Beautifier Maastricht (after)
These pictures are from Beautifier Maastricht
Profhilo picture of SW Clinic (before)
Profhilo picture of SW Clinic (after)
These pictures are from SW Clinic
Profhilo picture of Huidkliniek Twente (before)
Profhilo picture of Huidkliniek Twente (after)
These pictures are from Huidkliniek Twente
Profhilo picture of Moerman Clinic (before)
Profhilo picture of Moerman Clinic (after)
These pictures are from Moerman Clinic
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of SkinSurgery Clinics Den Haag (before)
Profhilo picture of SkinSurgery Clinics Den Haag (after)
These pictures are from SkinSurgery Clinics Den Haag
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics

How long does Profhilo last & safety

Effects can remain visible for up to 6–9 months. For longer-lasting results, two treatments spaced 4–6 weeks apart are often recommended. Aftercare and proper skincare help maintain more durable results. Side effects are usually mild and short-lived.

Profhilo: who is it suitable / less suitable for

Suitable if:

  • You want a natural skin improvement

  • Your skin lacks hydration and elasticity

  • You do not want an intensive procedure

Less suitable if:

  • You are looking for immediate volume enhancement

  • You are pregnant or have certain skin conditions

  • You have an infection in the treatment area

How do you determine if Profhilo is right for you?

  1. 1 What is your goal: hydration or volume?
  2. 2 Do you have dynamic or static signs of aging?
  3. 3 Which areas require an experienced doctor?
  4. 4 Do you want temporary results or periodic maintenance?
  5. 5 Which doctor has experience with Profhilo?

Profhilo: prices, experiences & comparison

Profhilo prices vary by clinic, treatment area, and the experience of the doctor. Compare prices in your area to get a good sense of market value.

TreatmentUnitCity/countryPrice
Profhilo treatmentper 2 ml United Kingdom £ 50Lowest price
Profhilo treatmentper 2 ml United Kingdom £ 258Average price
Profhilo treatmentper 2 ml United Kingdom £ 800Highest price

Compare prices in your area

Compare on experience & price Make an appointment immediately

Profhilo experiences: what do people really pay attention to?

People mainly focus on a natural-looking result, clarity during the consultation, trust in the doctor, and transparency about risks. Context is more important than star ratings alone.

Profhilo compared with alternatives

Profhilo vs fillers:

Profhilo improves skin quality; fillers add volume.

Profhilo vs Botox:

Botox relaxes muscles, Profhilo hydrates and stimulates.

Reviews Profhilo

I had such a great experience with Ankita! My treatments were a chemical peel and Profhilo and was amazing from start to finish. Super friendly, really knowledgeable, and gave me the best advice about my skin. The treatments went really smoothly with no issues at all, and I already noticed a difference after the first week! I felt completely comfortable and... Show more »
I had such a great experience with Ankita! My treatments were a chemical peel and Profhilo and was amazing from start to finish. Super friendly, really knowledgeable, and gave me the best advice about my skin. The treatments went really smoothly with no issues at all, and I already noticed a difference after the first week! I felt completely comfortable and in good hands the whole time. Looking forward to continuing my treatments with her. Highly recommend! ✨ Show less »
9 March 2026 09:09
Profhilo love the results Emma explains the procedure from the outset. Takes her time no rushing. Very professional I am always really happy with the results. Highly recommend Emma ❤️
Samantha Stables
Aurora Beauty Aesthetics
9 March 2026 03:03
I loved it! My skin looks glossy, rejuvenated and naturally moisturised after having the Profhilo skin booster treatment with Ivan. I really recommend him!
7 March 2026 10:10
A brilliant experience as always, loving the new consulting room🕶️ Dr Cei explains the process clearly, always listening to what I want to achieve, and reminding me to ‘trust the process’ I can now clearly see the results of the Profhilo Structura and am very pleased 😍 Next procedure booked 👍 I would highly recommend Dr Cei she is amazing!
suzzanne whiting
Dr Cei Aesthetics
5 March 2026 17:05
I honestly wouldn’t trust anyone else with my aesthetics. Natalie and the girls are absolutely amazing. I’ve been going to them for my Botox, skin pen, Profhilo and Morpheus treatments and the care they give every single time is incredible. Natalie is so knowledgeable, patient and genuinely lovely. She always takes the time to talk everything through proper... Show more »
I honestly wouldn’t trust anyone else with my aesthetics. Natalie and the girls are absolutely amazing. I’ve been going to them for my Botox, skin pen, Profhilo and Morpheus treatments and the care they give every single time is incredible.

Natalie is so knowledgeable, patient and genuinely lovely. She always takes the time to talk everything through properly and makes sure you feel completely comfortable before doing anything. You never feel rushed and she really listens to what you want, which makes such a difference.

The whole team are so kind and welcoming and they always make you feel at ease. For me, it’s about trust and I completely trust them with my face. The results are always natural and exactly what I’m looking for.

I wouldn’t go anywhere else Show less »
Caroline Stephanie Young
Naturally Flawless Aesthetics
5 March 2026 14:02

Profhilo doctors & clinics comparison

A doctor’s expertise makes the difference in results, safety, and aftercare. Compare clinics in your area based on experience, treatment approach, and honest advice.

Cosmetic specialists in United Kingdom

Frequently booked
Lindsay Bridge
Lindsay Bridge
Profession
-
Botox zone from
-
Filler per ml from
£ 250,00
View this specialist
Frequently booked
Natalie Gladstone
Natalie Gladstone
Profession
-
Botox zone from
£ 135,00
Filler per ml from
£ 199,00
View this specialist
Michelle McLean
Michelle McLean
Profession
Advanced Nurse Practitioner
Botox zone from
£ 120,00
Filler per ml from
£ 250,00
View this specialist
Yiannis Valilas
Dr. Yiannis Valilas
Profession
-
Botox zone from
£ 250,00
Filler per ml from
£ 410,00
View this specialist
Ducu Botoaca
Dr. Ducu Botoaca
Profession
-
Botox zone from
-
Filler per ml from
-
View this specialist
Francis Banhidy
Dr. Francis Banhidy
Profession
General Practitioner
Botox zone from
£ 200,00
Filler per ml from
-
View this specialist
Lauren Wells
Dr. Lauren Wells
Profession
-
Botox zone from
£ 200,00
Filler per ml from
£ 350,00
View this specialist
Nabil Jetha
Dr. Nabil Jetha
Profession
Aesthetic Doctor
Botox zone from
£ 250,00
Filler per ml from
£ 350,00
View this specialist

Differences between clinics for Profhilo treatments

  • Consultation approach: Medical history and risk management

  • Price transparency: Clear pricing

  • Aftercare: Availability after treatment

Compare clinics in United Kingdom

Promoted
Top rated
Hampstead Aesthetics
Hampstead Aesthetics
London, West End Lane 269
Botox zone from
£ 180,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 300,00
View profile
Promoted
Recently booked
Lindsay Owens Aesthetics
Lindsay Owens Aesthetics
Sevenoaks, Plaxdale Green Road
Botox zone from
-
Filler per ml from
£ 250,00
Profhilo per 2 ml from
-
View profile
Promoted
Top rated
Laser Clinics UK - Plymouth
Laser Clinics UK - Plymouth
Plymouth, Charles Street 1
Botox zone from
£ 135,00
Filler per ml from
£ 199,00
Profhilo per 2 ml from
£ 325,00
View profile
Promoted
Top rated
Thérapie Clinic - Liverpool
Thérapie Clinic - Liverpool
Liverpool, South John Street 46a
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile
Promoted
Verified clinic
Laser Clinics UK - Manchester
Laser Clinics UK - Manchester
Manchester
Botox zone from
£ 135,00
Filler per ml from
£ 199,00
Profhilo per 2 ml from
£ 325,00
View profile
Promoted
Top rated
Thérapie Clinic - Marylebone
Thérapie Clinic - Marylebone
London, Wigmore Street
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile
Promoted
Top rated
Thérapie Clinic - Bath
Thérapie Clinic - Bath
Bath, Southgate Place 12
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile
Promoted
Top rated
Thérapie Clinic - Belfast
Thérapie Clinic - Belfast
Belfast, Ann Street 36
Botox zone from
£ 129,00
Filler per ml from
£ 250,00
Profhilo per 2 ml from
£ 259,00
View profile

Frequently asked questions about Profhilo

How long does Profhilo last?

What are the disadvantages of Profhilo?

What does Profhilo do to your face?

What should you not do after Profhilo?

What are the best fillers?

Can Profhilo be combined?

Profhilo is an effective and relatively gentle treatment for skin improvement and hydration with natural-looking results. Results vary per person and strongly depend on the expertise of the doctor. Compare doctors and clinics in your area to make the right choice. This information does not replace a personal consultation.

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