Profhilo treatment

12 August 2026
Tom van Eijk
The contents of this article is medically checked by: Drs. Tom van Eijk

Profhilo is an injectable hyaluronic acid treatment primarily used to support skin quality rather than create targeted facial volume. It may be considered when the treatment goal relates to hydration, elasticity, skin texture or mild skin laxity.

Profhilo contains stabilised complexes of high- and low-molecular-weight hyaluronic acid. Unlike a conventional dermal filler, the treatment is not primarily intended to fill a specific hollow, build a facial feature or make a defined change to facial contours.

Results and suitability vary between individuals. This page gives you a complete overview of Profhilo treatment in the UK. For specific questions about results, side effects, costs, treatment areas and practitioner selection, you can continue to the dedicated Profhilo guides.

Profhilo treatment

What is Profhilo?

Profhilo is an injectable product based on hyaluronic acid. The Profhilo product line uses what the manufacturer IBSA describes as Hybrid Cooperative Complexes of high- and low-molecular-weight hyaluronic acid produced using its NAHYCO technology.

The main distinction from many dermal fillers is the treatment goal. Profhilo is primarily considered for skin quality, hydration, elasticity and mild skin laxity rather than for deliberately adding volume to a specific facial feature.

For a more detailed explanation of the product and its formulation, see what is Profhilo?

Why Profhilo results vary

Profhilo results are influenced by your skin condition, age, hydration, degree of laxity, lifestyle and individual response to treatment.

Someone with mild dryness or early changes in skin elasticity may notice a different result from someone with more advanced laxity, deeper lines or facial volume loss. Profhilo is also unlikely to produce the immediate structural change associated with dermal fillers.

Changes in skin quality usually develop over several weeks. An initial course often includes two sessions, but the number and timing of treatments should be based on an individual consultation.

A suitable clinic should clearly explain the likely benefits, limitations, treatment timeline and whether another procedure may be more appropriate.

Read more: When do you see Profhilo results?

What does Profhilo do to the skin?

Profhilo is intended to influence characteristics associated with skin quality. Clinical research has examined outcomes including hydration, elasticity, skin laxity and wrinkle-related measures.

However, the available studies differ in design, size and outcome measures. This means treatment cannot guarantee a particular level of tightening, smoothing or visible improvement for an individual person.

Profhilo is not the same as dermal filler

A conventional hyaluronic acid dermal filler can be placed strategically to restore volume, support facial structure or change the contour of a particular area.

Profhilo has a different primary purpose and would not normally be selected when defined volume replacement or facial reshaping is the main treatment goal.

See the dedicated comparison of Profhilo vs fillers.

What to consider before choosing Profhilo

  1. 1 Decide whether your main goal is skin quality or additional volume
  2. 2 Identify the area and skin concern you want assessed
  3. 3 Ask how many treatment sessions may be appropriate
  4. 4 Check the practitioner's qualifications, registration and Profhilo experience
  5. 5 Ask what follow-up and aftercare are available

How many Profhilo treatments do you need?

Profhilo is commonly planned as a course of treatment rather than automatically as one standalone appointment.

An initial course of two treatments around four weeks apart is commonly used, but the appropriate schedule should still be based on the product being used, treatment area, previous treatment history, skin assessment and individual treatment plan.

A third session or later maintenance treatment should not automatically be assumed to be necessary.

For this specific question, see how many Profhilo treatments are needed.

When do you see results from Profhilo?

Profhilo should not be expected to produce the immediate structural change associated with a treatment specifically designed to add facial volume.

Early changes may relate to hydration or the way the skin feels, while changes in texture, firmness or elasticity may become easier to assess gradually over the following weeks.

Temporary swelling and small raised areas at injection points can also affect how the skin looks immediately after treatment, so the first few days should not be treated as the final result.

Read the full Profhilo results timeline.

Profhilo before and after: how should you assess photos?

Before-and-after photographs can help demonstrate the type and scale of change that may occur following Profhilo treatment, but photographs cannot predict your own outcome.

When comparing photos, check whether the lighting, camera distance, angle, facial position and expression are similar. You should also look at when the after photograph was taken and whether the person completed one treatment or a full treatment course.

Where possible, compare examples involving a starting skin concern reasonably similar to your own rather than selecting the most dramatic image.

View more Profhilo before-and-after photos.

Profhilo before and after

Profhilo picture of Beautifier Maastricht (before)
Profhilo picture of Beautifier Maastricht (after)
These pictures are from Beautifier Maastricht
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Dokter Lylian Logtenberg Kliniek (before)
Profhilo picture of Dokter Lylian Logtenberg Kliniek (after)
These pictures are from Dokter Lylian Logtenberg Kliniek
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Dikrama Clinics (before)
Profhilo picture of Dikrama Clinics (after)
These pictures are from Dikrama Clinics
Profhilo picture of ØSK Clinic (before)
Profhilo picture of ØSK Clinic (after)
These pictures are from ØSK Clinic
Profhilo picture of SkinSurgery Clinics Den Haag (before)
Profhilo picture of SkinSurgery Clinics Den Haag (after)
These pictures are from SkinSurgery Clinics Den Haag
Profhilo picture of Moerman Clinic (before)
Profhilo picture of Moerman Clinic (after)
These pictures are from Moerman Clinic
Profhilo picture of Prof. Aesthetics (before)
Profhilo picture of Prof. Aesthetics (after)
These pictures are from Prof. Aesthetics
Profhilo picture of Huidkliniek Twente (before)
Profhilo picture of Huidkliniek Twente (after)
These pictures are from Huidkliniek Twente

How long do Profhilo results last?

Profhilo does not produce a permanent cosmetic result. How long a noticeable change remains can differ depending on factors such as the starting condition of the skin, treatment area, treatment course, lifestyle and individual response.

Maintenance treatment may be discussed after an initial course, but the timing should be based on reassessment rather than assuming that everyone needs another treatment on the same fixed date.

Read more about how long Profhilo lasts.

What if you see little or no result from Profhilo?

Seeing little visible difference does not automatically mean that the injection was performed incorrectly or that the product has “failed”.

It may still be too early to assess the outcome, the change may be more subtle than expected, or Profhilo may not closely match the concern you originally wanted to address.

Discuss the result with the treating practitioner before automatically booking another session.

Read about possible explanations when Profhilo does not appear to work.

Which areas can be treated with Profhilo?

Profhilo is strongly associated with skin-quality treatment of the face and neck. The appropriate product, injection technique and treatment plan depend on the anatomical area and the concern being assessed.

Do not assume that the same Profhilo protocol should be used in every area of the face or body.

For area-specific guidance, see Profhilo for the face.

Profhilo for the neck and décolletage

The skin of the neck and décolletage differs from facial skin, so the practitioner needs to assess the degree of laxity, skin quality and expected benefit for the individual area.

For detailed treatment information, read about Profhilo for the neck.

Profhilo Body and Profhilo Structura

Profhilo is now a product family, and the different products should not be treated as interchangeable versions of the same procedure.

Profhilo Body is intended for selected body areas, while Profhilo Structura is a separate product with a different treatment purpose from conventional facial Profhilo.

Read the dedicated guide to Profhilo Body.

Who may consider Profhilo?

Profhilo may be discussed when the main treatment goal is a subtle improvement in skin quality without deliberately creating significant additional facial volume.

A practitioner should first assess whether your concern corresponds to what Profhilo is intended to address and whether there are medical, anatomical or skin-related reasons to change, delay or avoid treatment.

Profhilo is unlikely to be the most logical choice when the main aim is substantial volume replacement, a pronounced change in facial contour or treatment of a concern primarily caused by facial muscle movement.

Choosing not to have an injectable treatment is also a valid outcome of a consultation.

Profhilo safety and treatment considerations

What temporary reactions can occur after Profhilo?

When should you contact the treating clinic?

What should you tell your practitioner before Profhilo?

What can you do after a Profhilo treatment?

Follow the individual aftercare instructions given by the practitioner who treated you. Advice may differ depending on the treatment area, injection technique and how the skin responds immediately afterwards.

If you specifically want guidance about exercise, touching the area, skincare, make-up, alcohol, heat, saunas or other activities after treatment, see the full Profhilo aftercare guide.

Profhilo or another skin treatment?

Treatments discussed for skin ageing or skin quality do not necessarily work in the same way. The most useful comparison therefore starts with what you actually want the treatment to change.

Profhilo or skin booster?

Both may be discussed when hydration or general skin quality is a priority, but product composition, placement and treatment protocols differ. They should not automatically be treated as interchangeable terms.

Read the dedicated Profhilo vs skin boosters comparison.

What about Botox?

Botulinum toxin has a different mechanism of action and is primarily used for different indications. It is therefore not a direct substitute for Profhilo.

How much does Profhilo cost in the UK?

Profhilo prices vary between UK clinics and treatment plans.

When comparing prices, check more than the headline figure. Look at which Profhilo treatment is being offered, whether the price covers one session or a course, who performs the treatment, and whether consultation, review appointments and aftercare are included.

You can compare current information in the dedicated Profhilo cost comparison.

Found a Profhilo offer? What should you check?

A lower advertised price does not by itself tell you whether two Profhilo offers are equivalent.

Check whether the offer relates to standard Profhilo, Profhilo Body or Profhilo Structura, how many sessions are included, which area is being treated, and whether consultation, review and aftercare form part of the price.

See current information about Profhilo offers in the UK.

Compare Profhilo clinics near you

Compare on experience & price Make an appointment immediately

Profhilo reviews: what can patient experiences tell you?

Patient reviews can provide useful context about the consultation, communication, treatment experience, aftercare and how a clinic manages expectations.

A review cannot prove that you will achieve the same cosmetic outcome as another patient.

Rather than relying only on the overall star rating, read several detailed experiences and look for comments relevant to the complete treatment journey.

View Profhilo reviews.

Profhilo reviews in the UK

Nicole is exceptional! I had no previous experience with aesthetic treatments and had no idea what to expect. Nicole is so warm and welcoming and I felt totally at ease when explaining my concerns to her. I had botox and Profhilo treatments. These appointments were staggered, so I never experienced any discomfort or concerns. Nicole talked me through each... Show more »
Nicole is exceptional!
I had no previous experience with aesthetic treatments and had no idea what to expect. Nicole is so warm and welcoming and I felt totally at ease when explaining my concerns to her.
I had botox and Profhilo treatments.
These appointments were staggered, so I never experienced any discomfort or concerns. Nicole talked me through each procedure perfectly.
I am so happy with the results and will definitely be back in a couple of months for "maintenance "
Nicole - thank you for everything! Show less »
Antonia Mastrorilli
Nurse Nicole Aesthetics Ltd
24 July 2026 18:06
I had an amazing experience at this clinic! The team was professional, friendly, and made me feel completely comfortable throughout my Profhilo treatment. The results have been fantastic, and I couldn’t be happier. Without a doubt, this is one of the best places in London for Profhilo. I highly recommend it to anyone looking for exceptional care and beautifu... Show more »
I had an amazing experience at this clinic! The team was professional, friendly, and made me feel completely comfortable throughout my Profhilo treatment. The results have been fantastic, and I couldn’t be happier. Without a doubt, this is one of the best places in London for Profhilo. I highly recommend it to anyone looking for exceptional care and beautiful, natural-looking results. Show less »
17 July 2026 19:07
I couldn’t be happier with my Profhilo and Botox treatments. From the initial consultation, Dr Vineeta was incredibly knowledgeable, professional, and took the time to explain everything clearly, making me feel completely at ease. The results have exceeded my expectations. My skin looks healthier, smoother, and much more radiant, and I’ve had so many compli... Show more »
I couldn’t be happier with my Profhilo and Botox treatments. From the initial consultation, Dr Vineeta was incredibly knowledgeable, professional, and took the time to explain everything clearly, making me feel completely at ease.

The results have exceeded my expectations. My skin looks healthier, smoother, and much more radiant, and I’ve had so many compliments on how fresh and glowing it looks. The Botox has given me a natural, refreshed appearance without looking overdone, which is exactly what I wanted.

I highly recommend this clinic to anyone. I’ll definitely be returning for future treatments. Show less »
14 July 2026 12:12
Wonderful experience. Always feel very safe and in good hands. The Botox is really great and I never need a top up. Profhilo is also great and the procedure is done with care. Would 100 percent recommend.
10 July 2026 16:04
I visited Dr Kaur to improve the appearance of my skin in the lead-up to a family wedding. I had a skincare consultation followed by a few treatments, including Profhilo and a chemical peel. Dr Kaur immediately made me feel welcome and at ease. She is friendly, approachable and genuinely took the time to understand what I wanted to achieve, rather than reco... Show more »
I visited Dr Kaur to improve the appearance of my skin in the lead-up to a family wedding. I had a skincare consultation followed by a few treatments, including Profhilo and a chemical peel.

Dr Kaur immediately made me feel welcome and at ease. She is friendly, approachable and genuinely took the time to understand what I wanted to achieve, rather than recommending treatments I didn't need. This honesty and integrity really gave me confidence and trust in her advice. She also explained everything in a way that was easy to understand, including how to repair my skin barrier, which was so appreciated when there's so much conflicting information online!

Her attention to detail is also lovely, as she is so attentive during treatment, as well as checking up on you afterwards. She is so understanding of her clients and how busy life can be, which makes the whole experience feel supportive too.

I'm so pleased with the results I've achieved so far, and I'm looking forward to continuing my skincare journey with Dr Kaur! I wouldn't hesitate to recommend her to anyone looking for empathetic, knowledgeable and person-centred care! Show less »

How do you choose a Profhilo practitioner in the UK?

Professional registration is an important checkpoint, but registration by itself does not show how frequently someone assesses or performs Profhilo treatment.

Look at the practitioner's professional background, relevant Profhilo experience, quality of the consultation, explanation of alternatives and limitations, proposed treatment plan, aftercare arrangements and what happens if you have a concern after treatment.

On Injectablesbooking, practitioner profiles can show the practitioner's profession and registration number where provided, making it easier to check this information before booking. You can then verify registration with the relevant UK professional register.

See the complete guide to choosing a Profhilo practitioner.

Cosmetic specialists in United Kingdom

Top rated
Chike Emeagi
Dr. Chike Emeagi
Profession
Aesthetic Doctor
Profhilo from
£ 300,00
View this specialist
Top rated
Arun Karwal
Dr. Arun Karwal
Profession
Aesthetic Doctor
Profhilo from
£ 400,00
View this specialist
Frequently booked
Yvonne Ndefo
Dr. Yvonne Ndefo
Profession
Aesthetic Doctor
Profhilo from
£ 259,00
View this specialist
Frequently booked
Zara Katchi
Dr. Zara Katchi
Profession
Aesthetic Doctor
Profhilo from
£ 259,00
View this specialist
Top rated
Debbie Ellis
Debbie Ellis
Profession
Nurse prescriber (V300 Independent)
Profhilo from
£ 279,00
View this specialist
Frequently booked
Monaf Al-Samawi
Dr. Monaf Al-Samawi
Profession
Medical Doctor
Profhilo from
£ 325,00
View this specialist
Frequently booked
Tanya Vyland
Dr. Tanya Vyland
Frequently booked
Natalie Gladstone
Natalie Gladstone
Profession
Aesthetic Nurse Practitioner
Profhilo from
£ 325,00
View this specialist

How do you compare Profhilo clinics?

Compare clinics on more than one factor.

Relevant points include the practitioner performing the treatment, consultation quality, experience with Profhilo, treatment planning, transparent pricing, patient reviews, before-and-after photographs, follow-up arrangements and how easily the clinic can be contacted if a problem occurs.

The cheapest clinic is not automatically the most appropriate clinic for you. Equally, the clinic with the largest number of reviews is not necessarily the best fit for your particular treatment goal.

Injectablesbooking allows you to compare Profhilo clinics and practitioners across the UK using clinic profiles, practitioner information, prices where supplied, reviews and available treatment information.

For a more detailed checklist, see how to compare Profhilo clinics.

Compare clinics in United Kingdom

Promoted
Top rated
Hampstead Aesthetics
Hampstead Aesthetics
London, West End Lane 269
Profhilo from
£ 300,00
View profile
Promoted
Top rated
Karwal Aesthetics
Karwal Aesthetics
London, Dover Street 15
Profhilo from
£ 400,00
View profile
Doctor-led fillers and laser treatments in London
ProfhiloSculptra (per vial)
Recently 36x booked
Promoted
Top rated
Thérapie Clinic - Birmingham City Centre
Thérapie Clinic - Birmingham City Centre
Birmingham, Lower Temple Street
Profhilo from
£ 259,00
View profile
Helping you look and feel your best every day.
ProfhiloSculptra (per vial)
Recently 21x booked
Promoted
Top rated
Thérapie Clinic - Liverpool
Thérapie Clinic - Liverpool
Liverpool, South John Street 46a
Profhilo from
£ 259,00
View profile
Helping you look and feel your best every day.
ProfhiloSculptra (per vial)
Recently 38x booked
Promoted
Top rated
Thérapie Clinic - Bath
Thérapie Clinic - Bath
Bath, Southgate Place 12
Profhilo from
£ 259,00
View profile
Helping you look and feel your best every day.
ProfhiloSculptra (per vial)
Recently 23x booked
Promoted
Top rated
Thérapie Clinic - Belfast
Thérapie Clinic - Belfast
Belfast, Ann Street 36
Profhilo from
£ 259,00
View profile
Helping you look and feel your best every day.
ProfhiloSculptra (per vial)
Recently 21x booked
Promoted
Top rated
Thérapie Clinic - Bluewater, Kent
Thérapie Clinic - Bluewater, Kent
Greenhithe
Profhilo from
£ 259,00
View profile
Helping you look and feel your best every day.
ProfhiloSculptra (per vial)
Recently 25x booked
Promoted
Top rated
Thérapie Clinic - Brighton and Hove
Thérapie Clinic - Brighton and Hove
Hove, Western Road 98
Profhilo from
£ 259,00
View profile
Helping you look and feel your best every day.
ProfhiloSculptra (per vial)
Recently 25x booked

Frequently asked questions about Profhilo

What is a Profhilo treatment?

Is Profhilo the same as dermal filler?

When do you see results from Profhilo?

How many Profhilo treatments do you need?

What are the side effects of Profhilo?

How much does Profhilo cost in the UK?

Why might Profhilo appear not to work?

How do you choose a Profhilo practitioner?

Compare Profhilo treatment in the UK

Profhilo may be considered when your main goal relates to skin hydration, elasticity and overall skin quality without deliberately adding substantial facial volume.

Whether Profhilo is appropriate for your skin, anatomy and expectations should be assessed during an individual consultation.

Use Injectablesbooking to compare UK practitioners and clinics based on relevant experience, professional information, treatment approach, prices where available, patient reviews and aftercare.

A cosmetic treatment is always optional. Deciding not to proceed after a consultation remains a valid choice.

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