How long does Botox last?

  1. 1 How long does Botox work?
  2. 2 Find the best clinic near you
  3. 3 Read up on it: then you'll be well prepared

How long does Botox last?

Botox usually works for around 3 to 5 months. After several treatments, the effects can sometimes last a bit longer. To maintain the results, you’ll need occasional top-up treatments. If your muscles are stronger or your lines are deeper, you may need a new treatment every 3–4 months at the start.

On this page, you’ll find useful tips and can easily search for a clinic near you.

How long does Botox work?

A Botox treatment typically lasts around 3 to 4 months. However, the exact duration can vary from person to person. This depends on several factors:

• Individual differences
Do you have a strong frown line? That usually means the underlying muscle is powerful, and a higher dose may be needed to achieve the same result. On the other hand, if you’ve been having Botox for a few years, the overactive muscle becomes less dominant, so lower doses may be effective and the results may last longer.

• The practitioner
Every practitioner works slightly differently, and techniques can vary. For example, it’s important that the botulinum toxin is prepared correctly, injected in the right quantity, and placed with precision for the best results.

• The brand of botulinum toxin
Did you know that Botox is actually a brand name? It’s one of several brands of botulinum toxin used in cosmetic treatments. Other brands include Bocouture and Azzalure, and sometimes there are slight differences in how long each treatment remains effective.

How botulinum toxin works

Botox is derived from Clostridium botulinum and is a neurotoxin used in both cosmetic and medical treatments. The active ingredient, botulinum toxin, works by reducing muscle contractions, which helps to smooth wrinkles.

When injected, the toxin blocks the release of acetylcholine—a neurotransmitter that signals muscles to contract. This relaxation of the muscles softens wrinkles. Over time, the nerves regenerate, which is why the effect is always temporary.

You’ll usually start to notice results within a few days, with the full effect becoming visible after about two weeks. On average, the results last 3 to 4 months. Factors such as your metabolism, age, and the dosage used all influence how long Botox works for you.

𝑩𝒐𝒕𝒐𝒙 𝒇𝒆𝒊𝒕𝒆𝒏

Treatment time
15 minutes
Optimal operation
after 2 weeks
Expensive effect
3-4 months
How long does Botox last?

4 tips to make Botox last longer

Want your Botox treatment to work for as long as possible?
These simple tips can help:

• Keep moving your face
In the first few hours after treatment, try moving your facial muscles—frown, raise your eyebrows, look surprised, and smile. This helps the Botox spread and settle more effectively.

• Avoid touching the area
On the first day, try not to rub the treated areas. It’s also best to avoid bending forward, facial massages, exfoliation, intense exercise, saunas, or beauty treatments. And for the first four hours, don’t lie down or sleep.

• Start early
Beginning Botox preventatively can make results last longer. Lines that never form don’t need additional treatment later.

• Stay consistent
It might sound commercial, but regular treatments do help. If you don’t allow lines to fully return between sessions, the effects of Botox can last longer each time. This usually means fewer treatments are needed in the long run.

Watch the answer from Doctor Margaritha Adams of Waterland Clinic to the question: How long does Botox work?

What affects how long Botox lasts?

A Botox treatment doesn’t work in the same way for everyone. Several factors can influence how long the effects last.

Physical factors

  • Age: Older people often notice shorter-lasting results, as their skin has less elasticity.

  • Skin type: Those with thicker or oilier skin may find the effects wear off more quickly.

  • Muscle strength: Stronger facial muscles—such as a deep frown—may require higher doses, and results may not last as long.

  • Metabolism: People with a fast metabolism sometimes find that Botox wears off sooner.

Technical factors

  • Dosage: Higher doses can prolong results but may also increase the risk of side effects.

  • Practitioner’s experience: An experienced professional can deliver Botox more precisely, which can help the results last longer.

  • Injection technique: The correct depth and placement of injections play a big role in how effective and long-lasting the results are.

Lifestyle factors

  • Smoking: Smoking can weaken the skin, making Botox effects fade faster.

  • Alcohol consumption: Excessive alcohol can reduce the effectiveness of treatments.

  • Sun exposure: Frequent UV exposure accelerates skin ageing, which can shorten the benefits of Botox.

The discovery of botulinum toxin

Botulinum toxin has been used in medicine since the 1970s. It was first developed by ophthalmologists as a treatment for strabismus (squint), a condition caused by an imbalance in the eye muscles. Traditionally, patients had to undergo repeated eye surgeries, as weakened muscles stretched like elastic bands while their opposing muscles tightened, often leading to scarring and the need for further operations.

In search of a less invasive alternative, American ophthalmologist Dr Alan B. Scott began experimenting with botulinum toxin. By injecting it into the overactive eye muscle, he was able to relax it temporarily and correct the squint—without surgery. This breakthrough paved the way for the medical and cosmetic use of Botox today.

How botulinum toxin works

Botulinum toxin works by entering nerve cells and releasing an enzyme that prevents muscle contraction. Scientists have since discovered that the enzyme targets specific proteins inside the nerve endings, called SNARE proteins. These proteins form a complex at the junction between nerves and muscles, allowing signals to pass through.

The toxin cuts the SNARE proteins in two, disabling them. Without SNAREs, nerves can’t release the chemical messengers that tell muscles to contract. This effect is very local, which is why Botox can be used so precisely—for example, to smooth forehead lines, crow’s feet, or frown lines.

The blocking of SNARE proteins is permanent, but the effect of Botox is temporary. This is because nerve cells create new proteins over time, restoring the connection between nerve and muscle. This process takes around 12 weeks, after which muscle activity gradually returns and wrinkles reappear.

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Before and after photos

Voorhoofdsrimpels picture of Ivy clinics Den Bosch (before)
Voorhoofdsrimpels picture of Ivy clinics Den Bosch (after)
These pictures are from Ivy clinics Den Bosch
Voorhoofdsrimpels picture of Dutchinjectables Amstelveen (before)
Voorhoofdsrimpels picture of Dutchinjectables Amstelveen (after)
These pictures are from Dutchinjectables Amstelveen
Voorhoofdsrimpels picture of Visage Clinic (before)
Voorhoofdsrimpels picture of Visage Clinic (after)
These pictures are from Visage Clinic
Voorhoofdsrimpels picture of Aepril Clinics Utrecht (before)
Voorhoofdsrimpels picture of Aepril Clinics Utrecht (after)
These pictures are from Aepril Clinics Utrecht
Voorhoofdsrimpels picture of HUID Den Haag (before)
Voorhoofdsrimpels picture of HUID Den Haag (after)
These pictures are from HUID Den Haag
Voorhoofdsrimpels picture of Happy Fillers (before)
Voorhoofdsrimpels picture of Happy Fillers (after)
These pictures are from Happy Fillers
Voorhoofdsrimpels picture of Aepril Clinics Hengelo (before)
Voorhoofdsrimpels picture of Aepril Clinics Hengelo (after)
These pictures are from Aepril Clinics Hengelo
Voorhoofdsrimpels picture of Dream Fillers (before)
Voorhoofdsrimpels picture of Dream Fillers (after)
These pictures are from Dream Fillers
Voorhoofdsrimpels picture of Dikrama Clinics (before)
Voorhoofdsrimpels picture of Dikrama Clinics (after)
These pictures are from Dikrama Clinics
Voorhoofdsrimpels picture of Dikrama Clinics (before)
Voorhoofdsrimpels picture of Dikrama Clinics (after)
These pictures are from Dikrama Clinics

When should I have Botox again?

Noticing your Botox results starting to fade? You’ll usually see the first effects within a few days, with the best results around the two-week mark. After about 3 to 4 months, the effects gradually wear off.

Tip: Take a photo before your treatment, then again after three days, two weeks, and once more after 3 to 4 months. Take one photo with your face relaxed and another while actively tensing the treated muscles. This makes it much easier to compare the results over time.

After three to four months, the body creates new nerve endings. Muscle activity slowly returns, and wrinkles become visible again. That’s the right moment to ask your practitioner if it’s time for another Botox treatment.

How long does Botox last?

The effects vary depending on the person and the treatment area. For dynamic wrinkles such as frown lines or crow’s feet, results last around 3–4 months. For excessive sweating (hyperhidrosis), results last around 6 months. For migraines, Botox usually provides around 3 months of relief—after which the cosmetic effect may remain, but the migraines can return.

Cosmetic treatments with botulinum toxin include:

  • Brow lift

  • Touch-up treatments (to optimise results)

  • Downturned mouth corners

  • Gummy smile (showing too much gum when smiling)

  • Chin dimpling

  • Bunny lines (lines at the side of the nose)

  • Tip lift for the nose

  • Headache relief

  • Lip flip (slightly fuller lips without filler)

  • Hyperhidrosis (excessive sweating)

  • Frown lines

  • Forehead lines

  • Crow’s feet

  • Teeth grinding (bruxism)

  • Baby Botox

  • Nefertiti lift

  • Platysma bands (neck ageing)

  • Migraine

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Booking a Botox appointment

Extensive research has confirmed the safety and effectiveness of botulinum toxin. But since everyone’s facial muscles are different, the best results depend on choosing the right practitioner. What matters most to you—the most experienced doctor, the one with the best reviews, the most affordable option, or someone who works with your preferred brand of botulinum toxin?

Injectablesbooking.co.uk offers a complete overview of clinics and practitioners who provide Botox treatments. You can also search specifically for qualified cosmetic doctors. The website allows you to compare options transparently and independently, helping you choose the practitioner you feel most comfortable with. Compare, select, and book your next injectables treatment via Injectablesbooking.co.uk.

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FAQ how long does Botox work

How long does Botox last?

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What does Botox do in the long term?

How long does Botox last in frown lines?

How often per year Botox?

Can I make Botox last longer?

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