What is a cosmetic polynucleotide treatment?
A treatment with polynucleotides, sometimes also known as salmon sperm, skin booster DNA injections, or bio-revitalisation with polynucleotides, is a new way to naturally improve and rejuvenate the skin. The goal of this treatment is to restore skin quality, reduce signs of ageing, and give a fresh, healthy appearance.
What are polynucleotides?
Polynucleotides are natural building blocks of DNA and RNA that naturally occur in our bodies. In cosmetic treatments, they are used to hydrate and firm the skin, while stimulating the natural healing and renewal of skin cells. The polynucleotides used in these treatments are completely safe and are broken down by the body.
What does a polynucleotide treatment involve?
A polynucleotide treatment, also known as a salmon filler, is an innovative injectable or skin booster therapy that restores and rejuvenates the skin from within. Polynucleotides are biological molecules derived from salmon DNA, specifically from salmon sperm.
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What is PhilArt?
How does a polynucleotide treatment work?
During the treatment, polynucleotides are injected into the skin with fine needles. A polynucleotide treatment, sometimes called salmon sperm, is an innovative injectable or skin booster that restores and rejuvenates the skin from within.
Polynucleotides are biological molecules derived from salmon DNA (salmon sperm). The doctor focuses on areas where the skin needs extra support, such as the face, neck, hands, or décolleté.
Treatments around the eyes, for example for dark circles or fine lines, are among the popular PDRN treatments. Usually, 3 to 4 sessions are needed, spaced 2 to 4 weeks apart. Each session lasts about 30 minutes.
What is a PDRN treatment?
Polynucleotides is a complicated word. Many clinics describe this treatment as PN injections, PDRN treatment, biorevitalisers, or nucleotide treatment.
For which skin concerns is this treatment suitable?
This treatment is suitable for:
Reducing fine lines and wrinkles
Addressing sagging or dull skin
Repairing damaged skin, for example due to sun exposure
Improving skin texture and tone
Hydrating dry or dehydrated skin
The treatment is often recommended for people looking for a natural way to improve their skin without undergoing surgery.
What can you expect from ‘PDRN’?
Softer and fuller skin
Fewer fine lines and wrinkles
A healthy and radiant appearance
Some results are visible after the first treatment, but the full effect usually becomes noticeable after a few weeks.
Is polynucleotide safe?
A treatment with polynucleotides is considered safe for several reasons:
Use of natural substances: Polynucleotides are compounds that naturally occur in the body. They support skin cell repair without chemical or synthetic additives.
Biocompatibility: Polynucleotides are well tolerated by the body and carry a low risk of allergic reactions or rejection.
Clinical studies: Research supports the effectiveness and safety of polynucleotides in skin improvement. Side effects are usually mild and short-lived, such as redness, swelling, or bruising.
Treatment by specialists: The procedure is carried out by qualified professionals, which further increases safety.
Minimal invasiveness: The treatments do not require surgery and involve a short recovery time, lowering risks compared to invasive procedures.
If you are considering this treatment, discuss your options with a qualified specialist to ensure the right approach for your skin type and needs.
Advantages and disadvantages of a polynucleotide treatment
Advantages:
Natural skin improvement without surgery
Suitable for almost all skin types
Promotes deep hydration and skin repair
Disadvantages:
Multiple sessions needed for optimal results
Temporary swelling or redness after the treatment
Not suitable during pregnancy or for certain medical conditions
Reviews
Had a lovely experience with Dr. Mahvish at Therapia Clinic Belgravia. I had anti-wrinkle treatment in 3 areas and polynucleotide treatment, and I’m really happy with the results. Dr. Mahvish was professional, gentle and took the time to explain everything. Highly recommend
30 August 2026 11:11
I have been seeing Dr Sbah for treatment for my undereyes with polynucleotides. Ive just had my second session and I cant believe the insane results already. Dr Sbah is the perfect mix of friendly and warm yet professional and knowledgable. She makes me feel so comfortable and im so so glad I chose her for my first ever experience with aesthetics. Looking fo...
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I have been seeing Dr Sbah for treatment for my undereyes with polynucleotides. Ive just had my second session and I cant believe the insane results already. Dr Sbah is the perfect mix of friendly and warm yet professional and knowledgable. She makes me feel so comfortable and im so so glad I chose her for my first ever experience with aesthetics. Looking forward to booking in more treatments with her ❤️
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Uzma Afzal
Laser Clinics UK - Glasgow Silverburn26 August 2026 19:07
Michelle is absolutely amazing! I first met her last year and have since had skin boosters under my eyes and on my face, and I’ve now started polynucleotides. Michelle is so patient and always takes the time to explain everything clearly, which makes you feel completely comfortable and confident. I’m so happy with my treatments and would definitely recommend...
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Michelle is absolutely amazing! I first met her last year and have since had skin boosters under my eyes and on my face, and I’ve now started polynucleotides. Michelle is so patient and always takes the time to explain everything clearly, which makes you feel completely comfortable and confident. I’m so happy with my treatments and would definitely recommend her to anyone considering these treatments. 💕
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Anamaria Cernaut
Dollie Aesthetics | Botox | Lemon Bottle | Dermal Fillers | Profhilo | Polynucleotides | Cosmetic Injectables25 August 2026 15:03
I honestly cannot praise Melissa at Prestige in St Albans enough for her amazing work, professionalism and expertise.
From my very first consultation, Melissa was incredibly professional, honest and realistic about what treatments would work for me and, importantly, what wouldn’t. I never felt pressured and really appreciated her taking the time to explain...
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I honestly cannot praise Melissa at Prestige in St Albans enough for her amazing work, professionalism and expertise.
From my very first consultation, Melissa was incredibly professional, honest and realistic about what treatments would work for me and, importantly, what wouldn’t. I never felt pressured and really appreciated her taking the time to explain everything and show me genuine before-and-after results.
We decided on RF Microneedling and Polynucleotides over three sessions. I was initially a little apprehensive, but Melissa talked me through everything and made me feel completely at ease.
I have now had two sessions, and the results after just two months are already noticeable. My sagging jowls have improved, my neck feels firmer, my fine lines have softened and even my overall complexion and skin quality have improved.
Melissa is amazing at what she does. She is knowledgeable, honest and genuinely cares about achieving the best results for her clients. You can tell she really knows her treatments and takes great pride in her work.
I am so pleased with my results so far and can't wait to see the final results after my third session. I would highly recommend Melissa to anyone considering aesthetic treatments. She is absolutely fantastic! Show less »
From my very first consultation, Melissa was incredibly professional, honest and realistic about what treatments would work for me and, importantly, what wouldn’t. I never felt pressured and really appreciated her taking the time to explain everything and show me genuine before-and-after results.
We decided on RF Microneedling and Polynucleotides over three sessions. I was initially a little apprehensive, but Melissa talked me through everything and made me feel completely at ease.
I have now had two sessions, and the results after just two months are already noticeable. My sagging jowls have improved, my neck feels firmer, my fine lines have softened and even my overall complexion and skin quality have improved.
Melissa is amazing at what she does. She is knowledgeable, honest and genuinely cares about achieving the best results for her clients. You can tell she really knows her treatments and takes great pride in her work.
I am so pleased with my results so far and can't wait to see the final results after my third session. I would highly recommend Melissa to anyone considering aesthetic treatments. She is absolutely fantastic! Show less »
prayer arm
Prestige Medical Beauty St Albans15 August 2026 19:07
Amazing experience at The Skin Firm! After my subcision with polynucleotide treatment, I’ve seen great improvement in my skin texture and acne scars. The results are better than I expected. Thank you to Dr. Naren for your expertise and care. Highly recommended!
5 August 2026 14:02
As a Newbie to TMA, I have experienced an authentic and holistic assessment and rejuvenation treatment plan bespoke to my needs and based on the experience that Tara holds as an aesthetic practitioner. TMA Bourne truly offers a relaxed clinical environment in beautiful surroundings with flexible appointments times.
I would recommend TMA based on my recent tr...
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As a Newbie to TMA, I have experienced an authentic and holistic assessment and rejuvenation treatment plan bespoke to my needs and based on the experience that Tara holds as an aesthetic practitioner. TMA Bourne truly offers a relaxed clinical environment in beautiful surroundings with flexible appointments times.
I would recommend TMA based on my recent treatments and flawless service.
Thankyou Tara
Further to my initial review, I have just completed my third polynucleotide treatment to both under eye areas. Having researched about this rejuvenating treatment the results are both visible and gradual in my case, giving a naturally improved contour, where I can feel more confident about these common, problem areas.
From initial assessment to completion of treatment, I have had complete trust in Tara’s clinical care and I experience. I highly recommend TMA.
Thankyou Tara.
Adding my review following completion of a course of polynucleotides and tear trough procedure to address my under eye areas. These treatments working in different ways but complimentary of each other have resulted in significant improvements to these problem areas. I’m delighted with my results.
I would highly recommend TMA as a highly trained, ethical clinical service bespoke to the needs of the individual. Show less »
I would recommend TMA based on my recent treatments and flawless service.
Thankyou Tara
Further to my initial review, I have just completed my third polynucleotide treatment to both under eye areas. Having researched about this rejuvenating treatment the results are both visible and gradual in my case, giving a naturally improved contour, where I can feel more confident about these common, problem areas.
From initial assessment to completion of treatment, I have had complete trust in Tara’s clinical care and I experience. I highly recommend TMA.
Thankyou Tara.
Adding my review following completion of a course of polynucleotides and tear trough procedure to address my under eye areas. These treatments working in different ways but complimentary of each other have resulted in significant improvements to these problem areas. I’m delighted with my results.
I would highly recommend TMA as a highly trained, ethical clinical service bespoke to the needs of the individual. Show less »
julie lydon
TMA Clinic29 July 2026 14:02
I had the most amazing experience at The Lodsworth clinic in the lead up to my wedding. I was nervous about getting any treatments, having never had injectables, but felt in such safe hands. Wendy came up with a manageable treatment plan to get me to my treatment goals. I couldn’t have felt in safer or more knowledgable hands and ended up with the most natur...
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I had the most amazing experience at The Lodsworth clinic in the lead up to my wedding. I was nervous about getting any treatments, having never had injectables, but felt in such safe hands. Wendy came up with a manageable treatment plan to get me to my treatment goals. I couldn’t have felt in safer or more knowledgable hands and ended up with the most natural and refreshed look with the Botox I had with her and the lovely Becca did several polynucleotide and Morpheus treatments. The end result was such a transformation in a good way! I felt I looked tired and a bit dull looking in January. By July I had glowing skin and looked as if I’d caught up on the last 10 years of missed sleep. The make up artist at my wedding said how amazing my skin was. If you’re in any doubt, this is the clinic for you. Experienced highly professional doctors, providing natural results.
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The Yoga Doc
The Lodsworth Clinic22 July 2026 16:04
Had microneedling with polynucleotides done with Katie at SW aesthetics and have already seen such a difference to my skin after just 2 sessions with my acne’s scars fading and my skin having a much nicer glow! Katie is lovely and after a consultation, she recommended this treatment and explained the whole process clearly. A very welcoming salon to visit☺️
Holly Sherrie
SW Aesthetics22 July 2026 14:02
Claire has transformed my skin, I've been aging backwards since finding her! I've had many microneedling, polynucleotides and facials appointments with Claire and wouldn't go anywhere else now. She's exceptional at her job and a lovely person.
Claire's professionalism, care and honest approach sets her above the rest and she's an advanced and experienced reg...
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Claire has transformed my skin, I've been aging backwards since finding her! I've had many microneedling, polynucleotides and facials appointments with Claire and wouldn't go anywhere else now. She's exceptional at her job and a lovely person.
Claire's professionalism, care and honest approach sets her above the rest and she's an advanced and experienced registered nurse, who else would you let inject your face?!
If subtle enhancements are what you're after, with a qualified nurse in a clean and welcoming environment you needn't look further! Show less »
Claire's professionalism, care and honest approach sets her above the rest and she's an advanced and experienced registered nurse, who else would you let inject your face?!
If subtle enhancements are what you're after, with a qualified nurse in a clean and welcoming environment you needn't look further! Show less »
Emma Sutton
WinterSkin Aesthetics21 July 2026 17:05
Absolutely love my visits to Mor! The team are all so friendly and highly qualified and experienced, so I always feel in super safe hands from laser to microneedling to polynucleotides! The space is spotless and relaxing, the client care is second to none and I’ve never felt pushed toward more treatments or products. When I have questions or want advice it’s...
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Absolutely love my visits to Mor! The team are all so friendly and highly qualified and experienced, so I always feel in super safe hands from laser to microneedling to polynucleotides! The space is spotless and relaxing, the client care is second to none and I’ve never felt pushed toward more treatments or products. When I have questions or want advice it’s always really balanced and informative. I regularly recommend Mor with totally confidence. I’m excited to see the business continue to grow 💛 Also, check out my cute hat, protecting my face from the sun 😘
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Bethan Michael-Fox
Mor Clinic21 July 2026 16:04
I originally visited Dr Raquel for under eye polynucleotides after having consultations at two other clinics. As this was a new treatment for me, and such a delicate area, I wanted to make sure I was in the right hands. Unfortunately, I just didn’t come away from my previous consultations with that level of confidence. However, from the moment I walked into...
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I originally visited Dr Raquel for under eye polynucleotides after having consultations at two other clinics. As this was a new treatment for me, and such a delicate area, I wanted to make sure I was in the right hands. Unfortunately, I just didn’t come away from my previous consultations with that level of confidence. However, from the moment I walked into Dr Raquel’s clinic, I had a completely different feeling. The atmosphere is professional, calm and welcoming, and I instantly felt comfortable and confident that I was in safe hands.
Dr Raquel is incredibly knowledgeable, warm, and approachable and takes the time to explain everything thoroughly. During my initial consultation, I learned so much about my skin and was given personalised recommendations that I’ve continued to follow, which have made a real difference to my skin’s dryness. She also talked me through the possible downtime and even showed me photos of what to expect after polynucleotides, something that hadn’t been mentioned during my previous consultations. It really showed how thorough she is and how much she genuinely cares about making sure her patients are fully informed and prepared.
I was quite nervous about having polynucleotides, but Dr Raquel completely put me at ease. Every step of the procedure was explained, and as someone who’s a complete wimp when it comes to treatments, I can honestly say there was nothing to worry about.
I’ve now had three polynucleotide treatments, as well as other procedures, and I’ve been so impressed with the results and the professionalism throughout. While the clinic is more expensive than some others, it is absolutely worth every penny for the expertise, care and peace of mind you receive.
A special mention also goes to Natalie, who is so friendly and welcoming. The aftercare is fantastic too, they genuinely care about their patients and always check in afterwards to make sure you’re recovering well and to answer any questions.
I wouldn’t hesitate to return or recommend Dr Raquel to anyone looking for expert, honest, and high quality aesthetic care. Thank you Dr Raquel. Show less »
Dr Raquel is incredibly knowledgeable, warm, and approachable and takes the time to explain everything thoroughly. During my initial consultation, I learned so much about my skin and was given personalised recommendations that I’ve continued to follow, which have made a real difference to my skin’s dryness. She also talked me through the possible downtime and even showed me photos of what to expect after polynucleotides, something that hadn’t been mentioned during my previous consultations. It really showed how thorough she is and how much she genuinely cares about making sure her patients are fully informed and prepared.
I was quite nervous about having polynucleotides, but Dr Raquel completely put me at ease. Every step of the procedure was explained, and as someone who’s a complete wimp when it comes to treatments, I can honestly say there was nothing to worry about.
I’ve now had three polynucleotide treatments, as well as other procedures, and I’ve been so impressed with the results and the professionalism throughout. While the clinic is more expensive than some others, it is absolutely worth every penny for the expertise, care and peace of mind you receive.
A special mention also goes to Natalie, who is so friendly and welcoming. The aftercare is fantastic too, they genuinely care about their patients and always check in afterwards to make sure you’re recovering well and to answer any questions.
I wouldn’t hesitate to return or recommend Dr Raquel to anyone looking for expert, honest, and high quality aesthetic care. Thank you Dr Raquel. Show less »
18 July 2026 09:09
I’ve been using Danielle for several years now and wouldn’t go anywhere else. She advises me on the best treatments for my skin type and is always super professional. I have a mix of Botox & polynucleotide injections which gives me back the freshness in my skin that has dimmed over the years. I wouldn’t hesitate to recommend Danielle and Barstable for any ae...
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I’ve been using Danielle for several years now and wouldn’t go anywhere else. She advises me on the best treatments for my skin type and is always super professional. I have a mix of Botox & polynucleotide injections which gives me back the freshness in my skin that has dimmed over the years. I wouldn’t hesitate to recommend Danielle and Barstable for any aesthetic treatments.
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Kerry Hobbs
Barstable17 July 2026 14:02
I first took my child to see Bec for skin tag removal after finding her online and being impressed by her professional credentials. From the very first appointment, I found her to be kind, knowledgeable, professional, and incredibly reassuring. The treatment was excellent, and based on that experience I booked a skin consultation for myself.
The consultatio...
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I first took my child to see Bec for skin tag removal after finding her online and being impressed by her professional credentials. From the very first appointment, I found her to be kind, knowledgeable, professional, and incredibly reassuring. The treatment was excellent, and based on that experience I booked a skin consultation for myself.
The consultation was one of the most thorough I’ve ever had. It was immediately clear how passionate and committed Bec is to achieving the best results for her clients. She took the time to understand exactly what I wanted to improve and created a detailed treatment plan tailored to my goals. Every option was carefully considered and fully explained, with transparent timelines, costs, and different budget options. There was absolutely no pressure, and I really appreciated how honest she was about what could realistically be achieved.
So far, I’ve had anti-wrinkle treatment, RF microneedling, polynucleotides, and HIFU. The results have genuinely surpassed my expectations. My skin has never looked better, my rosacea is under control for the first time in years, and the concerns I had about lines and overall skin quality have improved beyond what I thought possible. My skin is firmer, glowing, and the HIFU has made a huge difference to lifting my neck and jaw area.
Bec has been brilliant throughout the treatments. She is not only exceptionally skilled and knowledgeable but also genuinely lovely. I would recommend her without hesitation to anyone looking for honest advice a personalised treatment plan, and outstanding results. Show less »
The consultation was one of the most thorough I’ve ever had. It was immediately clear how passionate and committed Bec is to achieving the best results for her clients. She took the time to understand exactly what I wanted to improve and created a detailed treatment plan tailored to my goals. Every option was carefully considered and fully explained, with transparent timelines, costs, and different budget options. There was absolutely no pressure, and I really appreciated how honest she was about what could realistically be achieved.
So far, I’ve had anti-wrinkle treatment, RF microneedling, polynucleotides, and HIFU. The results have genuinely surpassed my expectations. My skin has never looked better, my rosacea is under control for the first time in years, and the concerns I had about lines and overall skin quality have improved beyond what I thought possible. My skin is firmer, glowing, and the HIFU has made a huge difference to lifting my neck and jaw area.
Bec has been brilliant throughout the treatments. She is not only exceptionally skilled and knowledgeable but also genuinely lovely. I would recommend her without hesitation to anyone looking for honest advice a personalised treatment plan, and outstanding results. Show less »
16 July 2026 18:06
I have just had my second round of Polynucleotides under eye treatment. Liam is incredible. Very professional and made me feel at ease throughout both visits. He explained the procedure in detail prior to having it and went through everything I needed to know after the treatment. I have no concerns after my treatment. My under eyes are looking and feelin...
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I have just had my second round of Polynucleotides under eye treatment. Liam is incredible. Very professional and made me feel at ease throughout both visits. He explained the procedure in detail prior to having it and went through everything I needed to know after the treatment. I have no concerns after my treatment. My under eyes are looking and feeling a lot better. Still have one more treatment to go before I can see the final results. I would definately recommend Liam and Nurseasthetics.
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Marie Claire Brandao
Nursethetics13 July 2026 14:02
I had polynucleotide injections with Stacy and I’m already seeing a massive difference, especially in the baggy skin on my eyelids. I’m so impressed with the results so far — the area already looks smoother, firmer, and much more refreshed.
Stacy was professional, knowledgeable, and made me feel completely at ease throughout the treatment. She explained ever...
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I had polynucleotide injections with Stacy and I’m already seeing a massive difference, especially in the baggy skin on my eyelids. I’m so impressed with the results so far — the area already looks smoother, firmer, and much more refreshed.
Stacy was professional, knowledgeable, and made me feel completely at ease throughout the treatment. She explained everything clearly and the whole experience felt really comfortable and reassuring. I’m so happy with the improvement already that I’ll definitely be booking my second treatment with her.
Highly recommend Stacy if you’re considering polynucleotide treatments! Show less »
Stacy was professional, knowledgeable, and made me feel completely at ease throughout the treatment. She explained everything clearly and the whole experience felt really comfortable and reassuring. I’m so happy with the improvement already that I’ll definitely be booking my second treatment with her.
Highly recommend Stacy if you’re considering polynucleotide treatments! Show less »
Claire Russell
Youthful Glow Aesthetics 7 July 2026 18:06
Oh, how I glow!
I have just finished my 3 course Polynucleotide Therapy, and although the treatment is still doing its thing, I have noticed such a difference to the tone and hydration of my skin. Especially my neck, which looks years younger.
Thanks Jo. You are a miracle worker!
I have just finished my 3 course Polynucleotide Therapy, and although the treatment is still doing its thing, I have noticed such a difference to the tone and hydration of my skin. Especially my neck, which looks years younger.
Thanks Jo. You are a miracle worker!
Lesley Todd
Glass Skin 6 July 2026 12:12
Just went to have polynucleotides and baby Botox. As ever, Kelsey did an amazing job. No swelling even in the heat. I would not trust my face with anyone else. If you are new and looking for a great practitioner to support good natural results, KB Aesthetics is the place to go!
Christine
KB Aesthetics London Ltd 3 July 2026 16:04
I recently visited Shumaila’s London Colchester for a microneedling and Polynucleotides session with Ganimete, and I couldn't be happier. She was incredibly professional, walked me through the entire process, and made sure I was comfortable with the numbing cream. My skin is currently healing, but the customer service and professionalism were top-notch. I...
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I recently visited Shumaila’s London Colchester for a microneedling and Polynucleotides session with Ganimete, and I couldn't be happier. She was incredibly professional, walked me through the entire process, and made sure I was comfortable with the numbing cream. My skin is currently healing, but the customer service and professionalism were top-notch. I can't wait to see the results over the next few days. ❤️
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G McDonagh Tomlin
Shumaila's London Colchester | Hyperpigmentation, Melasma, Hair Loss, Skin Tag Removal Treatment 3 July 2026 12:12
I've visited a few aesthetics practitioners over the years and Kayleigh is hands down the best. She makes you feel at ease right away and explains everything perfectly. She uses the best products and unboxes them in front of you so you know that you're getting the actual product your paying for. I'm not good with needles but as she treats you she talks you t...
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I've visited a few aesthetics practitioners over the years and Kayleigh is hands down the best. She makes you feel at ease right away and explains everything perfectly. She uses the best products and unboxes them in front of you so you know that you're getting the actual product your paying for. I'm not good with needles but as she treats you she talks you through the process while you get to pummel her P.L.A stress ball! 😳 It really does make the overall experience super pleasant. 🥰 I've had botox, polynucleotides and filler over the years with Kayleigh. Ever single time I've been thrilled with the outcome. Her botox results are exceptional. I've had some bad experiences with botox cowboys in the past and I would never go elsewhere now. Thank you Kayleigh and see you again soon for my next treatment 💕
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Tracy Thomason
Pretty little aesthetics P|L|A 2 July 2026 08:08
From the initial warm welcome, I felt completely relaxed and at home at Dr. Caroline Warden Skin clinic in hale.
I was able to talk freely about my aesthetic concerns whilst she did a thorough deep dive into all my available options and gave me a recommended skin and treatment plan. There was absolutely no pressure to jump into anything, which I really appr...
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From the initial warm welcome, I felt completely relaxed and at home at Dr. Caroline Warden Skin clinic in hale.
I was able to talk freely about my aesthetic concerns whilst she did a thorough deep dive into all my available options and gave me a recommended skin and treatment plan. There was absolutely no pressure to jump into anything, which I really appreciated. They encouraged me to take my time and think about my options before booking treatments. This gave me a lot of confidence in their professionalism.
Since then, I’ve come back a few times and had Botox, some Profhilo skin boosters, and started polynucleotides under my eyes. I’m even considering cheek filler next! Every single treatment has gone well, and I’ve felt so well looked after.
They even text me the next day to check in on how I’m doing. I genuinely can’t say a single negative thing. I recommend this Hale aesthetic clinic now to all my friends and family, honestly they’re simply the best!! If you’re on the fence like I was… just go for it. Zero regrets! Show less »
I was able to talk freely about my aesthetic concerns whilst she did a thorough deep dive into all my available options and gave me a recommended skin and treatment plan. There was absolutely no pressure to jump into anything, which I really appreciated. They encouraged me to take my time and think about my options before booking treatments. This gave me a lot of confidence in their professionalism.
Since then, I’ve come back a few times and had Botox, some Profhilo skin boosters, and started polynucleotides under my eyes. I’m even considering cheek filler next! Every single treatment has gone well, and I’ve felt so well looked after.
They even text me the next day to check in on how I’m doing. I genuinely can’t say a single negative thing. I recommend this Hale aesthetic clinic now to all my friends and family, honestly they’re simply the best!! If you’re on the fence like I was… just go for it. Zero regrets! Show less »
Louisa Wicks
Dr Caroline Warden Skin & Aesthetic Clinic30 June 2026 11:11
I wouldn’t go anywhere else for my beauty treatments…
I have my Botox every 4 months or so and recently had the new eye polynucleotide treatment and although I was nervous, Jo was, as always extremely professional and made me feel at ease.
She uses the best quality products and it’s obvious she has years of medical experience as she is extremely gentle yet e...
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I wouldn’t go anywhere else for my beauty treatments…
I have my Botox every 4 months or so and recently had the new eye polynucleotide treatment and although I was nervous, Jo was, as always extremely professional and made me feel at ease.
She uses the best quality products and it’s obvious she has years of medical experience as she is extremely gentle yet efficient.
Her aesthetics practice is beautiful. Show less »
I have my Botox every 4 months or so and recently had the new eye polynucleotide treatment and although I was nervous, Jo was, as always extremely professional and made me feel at ease.
She uses the best quality products and it’s obvious she has years of medical experience as she is extremely gentle yet efficient.
Her aesthetics practice is beautiful. Show less »
Gem Amron
Jo Wright29 June 2026 12:12
I had polynucleotide treatment with Emily yesterday and couldn’t be happier with my experience. Her knowledge and expertise were evident from the moment I arrived. She took the time to thoroughly explain the treatment, how it works, and what results I could expect, which made me feel completely confident and at ease.
Her attention to detail, professionalism,...
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I had polynucleotide treatment with Emily yesterday and couldn’t be happier with my experience. Her knowledge and expertise were evident from the moment I arrived. She took the time to thoroughly explain the treatment, how it works, and what results I could expect, which made me feel completely confident and at ease.
Her attention to detail, professionalism, and gentle approach throughout the procedure were exceptional. She answered all of my questions with confidence and demonstrated a deep understanding of aesthetics and skin health.
I would highly recommend Emily to anyone considering aesthetic treatments. Her skill, knowledge, and genuine care for her clients really sets her apart. I’m looking forward to seeing the results of my treatment and returning for future treatments. Show less »
Her attention to detail, professionalism, and gentle approach throughout the procedure were exceptional. She answered all of my questions with confidence and demonstrated a deep understanding of aesthetics and skin health.
I would highly recommend Emily to anyone considering aesthetic treatments. Her skill, knowledge, and genuine care for her clients really sets her apart. I’m looking forward to seeing the results of my treatment and returning for future treatments. Show less »
Claire Leeming
EJW Aesthetics & Training24 June 2026 08:08
I had a wonderful experience with Dr. Carol. From the moment I arrived, I felt welcomed and completely at ease. She was professional, knowledgeable, and took the time to listen to my concerns and explain the treatment in detail, I had polynucleotides treatment.
What impressed me most was her attention to detail and honest approach. I felt confident that I w...
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I had a wonderful experience with Dr. Carol. From the moment I arrived, I felt welcomed and completely at ease. She was professional, knowledgeable, and took the time to listen to my concerns and explain the treatment in detail, I had polynucleotides treatment.
What impressed me most was her attention to detail and honest approach. I felt confident that I was in safe and experienced hands throughout the entire process.
I would highly recommend Dr. Carol to anyone looking for a skilled and caring aesthetic practitioner. Show less »
What impressed me most was her attention to detail and honest approach. I felt confident that I was in safe and experienced hands throughout the entire process.
I would highly recommend Dr. Carol to anyone looking for a skilled and caring aesthetic practitioner. Show less »
Silvia Bonino
Wrinkless - medical aesthetic clinic21 June 2026 18:06
I recently visited Aesthetics by Amo for polynucleotides under my eyes and jawline filler, and I’m so pleased with the results. Amo was professional, knowledgeable and made me feel at ease throughout the entire process.
Everything was explained clearly, and I felt confident I was in safe hands. I would highly recommend Aesthetics by Amo to anyone considerin...
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I recently visited Aesthetics by Amo for polynucleotides under my eyes and jawline filler, and I’m so pleased with the results. Amo was professional, knowledgeable and made me feel at ease throughout the entire process.
Everything was explained clearly, and I felt confident I was in safe hands. I would highly recommend Aesthetics by Amo to anyone considering aesthetic treatments and will definitely be returning in the future! Show less »
Everything was explained clearly, and I felt confident I was in safe hands. I would highly recommend Aesthetics by Amo to anyone considering aesthetic treatments and will definitely be returning in the future! Show less »
Amy Stiff
Aesthetics by Amo21 June 2026 10:10
I cannot recommend Ametrine enough!! I’ve just completed a course of polynucleotides and microneedling with Bryony and Hannah and they have transformed my skin. From the first consultation with Bryony I felt so at ease. She is so knowledgable and explained all potential treatment options for my skin concerns without me ever feeling pressured to go through wi...
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I cannot recommend Ametrine enough!! I’ve just completed a course of polynucleotides and microneedling with Bryony and Hannah and they have transformed my skin. From the first consultation with Bryony I felt so at ease. She is so knowledgable and explained all potential treatment options for my skin concerns without me ever feeling pressured to go through with anything. All of the girls there are so lovely and make you feel so comfortable during your appointment (and even laugh through the pain!). They also designed a personalised skincare plan for me which I really appreciated. The space itself is so calming, you can really see how much thought and attention to detail has been put into it.
Consider me a client for life I won’t be going anywhere else ❤️ Show less »
Consider me a client for life I won’t be going anywhere else ❤️ Show less »
Beth Poole
Ametrine Aesthetics20 June 2026 15:03
FAQ
Is the treatment painful?
The injections may be slightly sensitive, but a numbing cream is usually applied to make the procedure comfortable.
How long do the results last?
The effects usually last 6 to 12 months, depending on your skin type and lifestyle.
Are there any risks?
The treatment is generally safe. Redness, swelling, or bruising usually disappears within a few days.
What does a treatment cost?
The costs vary per clinic, but are often between £260 and £520 per session.
Which clinics in the United Kingdom offer this treatment?
On Injectablesbooking, you can easily find clinics that offer this treatment. The platform provides an overview of recognised clinics and GMC-registered doctors. Compare clinics based on experience, prices, and reviews to make the best choice.
Compare clinics in London
Promoted
Top rated
4.9
(1503 reviews)
Londen, Kings Road 558
5 km
- Botox zone from
- £ 225,00
- Filler per ml from
- £ 365,00
- Profhilo per 2 ml from
- -
Promoted
Top rated
4.8
(201 reviews)
London, West End Lane 269
7 km
- Botox zone from
- £ 180,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 300,00
Promoted
Top rated
London, Dover Street 15
1 km
- Botox zone from
- £ 300,00
- Filler per ml from
- £ 450,00
- Profhilo per 2 ml from
- £ 400,00
Promoted
Top rated
4.6
(4081 reviews)
London, Wigmore Street
2 km
- Botox zone from
- £ 129,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 195,00
Promoted
Top rated
4.6
(2870 reviews)
London
6 km
- Botox zone from
- £ 129,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 195,00
Promoted
Top rated
4.6
(2503 reviews)
London, Cabot Square 1
7 km
- Botox zone from
- £ 129,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 195,00
London, Pall Mall 120
<1 km
- Botox zone from
- -
- Filler per ml from
- £ 400,00
- Profhilo per 2 ml from
- £ 300,00
London, St James's Street 20
<1 km
- Botox zone from
- £ 230,00
- Filler per ml from
- £ 380,00
- Profhilo per 2 ml from
- £ 280,00
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