What is a cosmetic polynucleotide treatment?
A treatment with polynucleotides, sometimes also known as salmon sperm, skin booster DNA injections, or bio-revitalisation with polynucleotides, is a new way to naturally improve and rejuvenate the skin. The goal of this treatment is to restore skin quality, reduce signs of ageing, and give a fresh, healthy appearance.
What are polynucleotides?
Polynucleotides are natural building blocks of DNA and RNA that naturally occur in our bodies. In cosmetic treatments, they are used to hydrate and firm the skin, while stimulating the natural healing and renewal of skin cells. The polynucleotides used in these treatments are completely safe and are broken down by the body.
What does a polynucleotide treatment involve?
A polynucleotide treatment, also known as a salmon filler, is an innovative injectable or skin booster therapy that restores and rejuvenates the skin from within. Polynucleotides are biological molecules derived from salmon DNA, specifically from salmon sperm.
Read more:
What is PhilArt?
How does a polynucleotide treatment work?
During the treatment, polynucleotides are injected into the skin with fine needles. A polynucleotide treatment, sometimes called salmon sperm, is an innovative injectable or skin booster that restores and rejuvenates the skin from within.
Polynucleotides are biological molecules derived from salmon DNA (salmon sperm). The doctor focuses on areas where the skin needs extra support, such as the face, neck, hands, or décolleté.
Treatments around the eyes, for example for dark circles or fine lines, are among the popular PDRN treatments. Usually, 3 to 4 sessions are needed, spaced 2 to 4 weeks apart. Each session lasts about 30 minutes.
What is a PDRN treatment?
Polynucleotides is a complicated word. Many clinics describe this treatment as PN injections, PDRN treatment, biorevitalisers, or nucleotide treatment.
For which skin concerns is this treatment suitable?
This treatment is suitable for:
Reducing fine lines and wrinkles
Addressing sagging or dull skin
Repairing damaged skin, for example due to sun exposure
Improving skin texture and tone
Hydrating dry or dehydrated skin
The treatment is often recommended for people looking for a natural way to improve their skin without undergoing surgery.
What can you expect from ‘PDRN’?
Softer and fuller skin
Fewer fine lines and wrinkles
A healthy and radiant appearance
Some results are visible after the first treatment, but the full effect usually becomes noticeable after a few weeks.
Is polynucleotide safe?
A treatment with polynucleotides is considered safe for several reasons:
Use of natural substances: Polynucleotides are compounds that naturally occur in the body. They support skin cell repair without chemical or synthetic additives.
Biocompatibility: Polynucleotides are well tolerated by the body and carry a low risk of allergic reactions or rejection.
Clinical studies: Research supports the effectiveness and safety of polynucleotides in skin improvement. Side effects are usually mild and short-lived, such as redness, swelling, or bruising.
Treatment by specialists: The procedure is carried out by qualified professionals, which further increases safety.
Minimal invasiveness: The treatments do not require surgery and involve a short recovery time, lowering risks compared to invasive procedures.
If you are considering this treatment, discuss your options with a qualified specialist to ensure the right approach for your skin type and needs.
Advantages and disadvantages of a polynucleotide treatment
Advantages:
Natural skin improvement without surgery
Suitable for almost all skin types
Promotes deep hydration and skin repair
Disadvantages:
Multiple sessions needed for optimal results
Temporary swelling or redness after the treatment
Not suitable during pregnancy or for certain medical conditions
Reviews
Lovely clinic and friendly staff. I’ve had 3 sessions of undereye polynucleotides with Dr Maryam and really happy with the results!
Rebekah C Onyenuforo
KONCEPT Medical Clinic20 June 2026 11:11
I would highly recommend Bellissima Faces. I have had several treatments over the past two months in preparation for my wedding including Botox, microneedling, polynucleotides and lemon bottle fat dissolving. Bella is so warm and welcoming which has helped to ease any anxieties I may have had, having never been brave enough to try aesthetic treatments befo...
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I would highly recommend Bellissima Faces. I have had several treatments over the past two months in preparation for my wedding including Botox, microneedling, polynucleotides and lemon bottle fat dissolving. Bella is so warm and welcoming which has helped to ease any anxieties I may have had, having never been brave enough to try aesthetic treatments before. She is also extremely knowledgeable and an expert in her craft who upholds the highest standards of practice right through from infection control, patient experience, aftercare advice and so on. My work colleagues have all commented on how my skin is glowing recently 😊
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Laura Fox
Belissima17 June 2026 18:06
I had the absolute pleasure of visiting Dr. Aldo’s clinic for Botox and Polynucleotide treatments, and I couldn’t be happier with my experience.
From the moment I walked into the clinic, I was welcomed with professionalism, warmth, and exceptional attention to detail. Dr. Aldo took the time to thoroughly explain every step of the procedures, ensuring I felt...
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I had the absolute pleasure of visiting Dr. Aldo’s clinic for Botox and Polynucleotide treatments, and I couldn’t be happier with my experience.
From the moment I walked into the clinic, I was welcomed with professionalism, warmth, and exceptional attention to detail. Dr. Aldo took the time to thoroughly explain every step of the procedures, ensuring I felt comfortable, informed, and confident throughout.
The Botox treatment was virtually painless, and the Polynucleotide treatment was performed with the utmost care and precision. Dr. Aldo’s expertise and gentle technique made the entire experience incredibly comfortable.
What truly sets Dr. Aldo apart is his dedication to achieving natural, beautiful results while prioritising patient safety and satisfaction. His knowledge, professionalism, and genuine care are evident in every aspect of his work.
I am extremely pleased with my results and would highly recommend Dr. Aldo to anyone considering Botox, Polynucleotides, or any aesthetic treatments. An outstanding practitioner and a wonderful experience from start to finish.
⭐️⭐️⭐️⭐️⭐️ Show less »
From the moment I walked into the clinic, I was welcomed with professionalism, warmth, and exceptional attention to detail. Dr. Aldo took the time to thoroughly explain every step of the procedures, ensuring I felt comfortable, informed, and confident throughout.
The Botox treatment was virtually painless, and the Polynucleotide treatment was performed with the utmost care and precision. Dr. Aldo’s expertise and gentle technique made the entire experience incredibly comfortable.
What truly sets Dr. Aldo apart is his dedication to achieving natural, beautiful results while prioritising patient safety and satisfaction. His knowledge, professionalism, and genuine care are evident in every aspect of his work.
I am extremely pleased with my results and would highly recommend Dr. Aldo to anyone considering Botox, Polynucleotides, or any aesthetic treatments. An outstanding practitioner and a wonderful experience from start to finish.
⭐️⭐️⭐️⭐️⭐️ Show less »
Georgiana Vlăsceanu
goaesthetix 4 June 2026 23:11
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I had a lovely experience at Dr and Skin in Bolton. I originally booked in for polynucleotides under eye treatment but after a thorough consultation with Faiza and Dr Ammar a more personalised treatment plan was recommended. I really appreciated the honest advice and the time taken to explain what would be most suitable for my skin.
I had NCTF u...
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I had a lovely experience at Dr and Skin in Bolton. I originally booked in for polynucleotides under eye treatment but after a thorough consultation with Faiza and Dr Ammar a more personalised treatment plan was recommended. I really appreciated the honest advice and the time taken to explain what would be most suitable for my skin.
I had NCTF under eye injections for dark under eye circles and SkinPen microneedling on my face as well as on a purple scar on my knee. The whole process was explained clearly by Faiza and I felt comfortable and well looked after throughout.
The clinic is beautiful and the team are warm, professional and incredibly knowledgeable. I would highly recommend Dr and Skin clinic to anyone looking for personalised treatments and genuine expert care. I’m excited to see my results continue to develop over the coming weeks and can’t wait to return! Show less »
I had a lovely experience at Dr and Skin in Bolton. I originally booked in for polynucleotides under eye treatment but after a thorough consultation with Faiza and Dr Ammar a more personalised treatment plan was recommended. I really appreciated the honest advice and the time taken to explain what would be most suitable for my skin.
I had NCTF under eye injections for dark under eye circles and SkinPen microneedling on my face as well as on a purple scar on my knee. The whole process was explained clearly by Faiza and I felt comfortable and well looked after throughout.
The clinic is beautiful and the team are warm, professional and incredibly knowledgeable. I would highly recommend Dr and Skin clinic to anyone looking for personalised treatments and genuine expert care. I’m excited to see my results continue to develop over the coming weeks and can’t wait to return! Show less »
saira
Dr and Skin 4 June 2026 16:04
I had the consultation with Dr Naren for my under eyes and discussed I wanted polynucleotide. He recommended a couple of options and was honest about how it could work with a darker complexion. I’d also mentioned that I have TMJ and he discussed masseter botox with me, to which he did gradual doses until I reached a desired outcome, whilst he ensured I maint...
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I had the consultation with Dr Naren for my under eyes and discussed I wanted polynucleotide. He recommended a couple of options and was honest about how it could work with a darker complexion. I’d also mentioned that I have TMJ and he discussed masseter botox with me, to which he did gradual doses until I reached a desired outcome, whilst he ensured I maintained symmetry and didn’t over inject so I still have a full jaw function. The results have been amazing along with the advice, care and treatment I received.
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Sameera Zaman
The Skin Firm - By Dr Naren29 May 2026 16:04
I had a polynucleotide treatment package with Rachel and I couldn’t be happier with the results. She was professional, knowledgeable, and made me feel completely comfortable throughout the whole process. She explained everything clearly and took the time to answer all my questions, which really put me at ease.
The results have been amazing — my skin looks f...
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I had a polynucleotide treatment package with Rachel and I couldn’t be happier with the results. She was professional, knowledgeable, and made me feel completely comfortable throughout the whole process. She explained everything clearly and took the time to answer all my questions, which really put me at ease.
The results have been amazing — my skin looks fresher, healthier, and much more rejuvenated. I’ve already noticed a real improvement in texture and glow. Rachel’s attention to detail and expertise really show in her work. I would highly recommend her to anyone considering treatment. Show less »
The results have been amazing — my skin looks fresher, healthier, and much more rejuvenated. I’ve already noticed a real improvement in texture and glow. Rachel’s attention to detail and expertise really show in her work. I would highly recommend her to anyone considering treatment. Show less »
lor thomp
RM Beauty & Aesthetics28 May 2026 17:05
As a Newbie to TMA, I have experienced an authentic and holistic assessment and rejuvenation treatment plan bespoke to my needs and based on the experience that Tara holds as an aesthetic practitioner. TMA Bourne truly offers a relaxed clinical environment in beautiful surroundings with flexible appointments times.
I would recommend TMA based on my recent tr...
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As a Newbie to TMA, I have experienced an authentic and holistic assessment and rejuvenation treatment plan bespoke to my needs and based on the experience that Tara holds as an aesthetic practitioner. TMA Bourne truly offers a relaxed clinical environment in beautiful surroundings with flexible appointments times.
I would recommend TMA based on my recent treatments and flawless service.
Thankyou Tara
Further to my initial review, I have just completed my third polynucleotide treatment to both under eye areas. Having researched about this rejuvenating treatment the results are both visible and gradual in my case, giving a naturally improved contour, where I can feel more confident about these common, problem areas.
From initial assessment to completion of treatment, I have had complete trust in Tara’s clinical care and I experience. I highly recommend TMA.
Thankyou Tara. Show less »
I would recommend TMA based on my recent treatments and flawless service.
Thankyou Tara
Further to my initial review, I have just completed my third polynucleotide treatment to both under eye areas. Having researched about this rejuvenating treatment the results are both visible and gradual in my case, giving a naturally improved contour, where I can feel more confident about these common, problem areas.
From initial assessment to completion of treatment, I have had complete trust in Tara’s clinical care and I experience. I highly recommend TMA.
Thankyou Tara. Show less »
julie lydon
TMA Clinic26 May 2026 17:05
I had 3 rounds of polynucleotides with Dr Coffey, and my first ever botox. As new to injectables I was a very nervy client, but Dr Coffey was warm and welcoming and put me at great ease. Such a fantastic experience, I would definitely recommend…and will be back!!
Helena Chaffer
Dr Coffey Skin25 May 2026 12:12
Nicola made me feel so at ease with my treatment. I was a bit anxious to get the polynucleotides under my eyes, but the whole procedure was painless and comfortable. I’m really happy with my results, from this and my Botox treatment, and completely trust Nicola to carry out my treatment in the future.
Therapy Pony
Dr NG Aesthetics20 May 2026 14:02
I’ve been going to Sabrina for a while now. I’ve had a number of treatments from her, polynucleotides, cheek filler, lip filler, anti wrinkle injections and I can hand on heart say she is the best. She is extremely knowledgable and constantly upskilling and learning more. I trust her implicitly with my face. On top of her skill and talent in aesthetics she i...
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I’ve been going to Sabrina for a while now. I’ve had a number of treatments from her, polynucleotides, cheek filler, lip filler, anti wrinkle injections and I can hand on heart say she is the best. She is extremely knowledgable and constantly upskilling and learning more. I trust her implicitly with my face. On top of her skill and talent in aesthetics she is also one of the loveliest people, she really cares about her clients and once you’ve been once you will continue to return to her!
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Chelsea Henderson
Breagha Aesthetics Health & Wellness Clinic18 May 2026 18:06
I had an amazing experience with Dr Raquel and honestly cannot recommend her and the clinic highly enough.
I initially booked a consultation for concerns around ageing skin and TMJ issues, having heard Botox in the jaw could help. I would quite happily have gone ahead and spent £400 on treatment, so what I received instead was incredibly refreshing and unexp...
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I had an amazing experience with Dr Raquel and honestly cannot recommend her and the clinic highly enough.
I initially booked a consultation for concerns around ageing skin and TMJ issues, having heard Botox in the jaw could help. I would quite happily have gone ahead and spent £400 on treatment, so what I received instead was incredibly refreshing and unexpected.
From the moment I walked into the clinic after a busy workday, I instantly felt calm. The clinic itself is beautiful, peaceful, serene, softly lit, with calming music and the loveliest aromatherapy scent throughout. Natalie was on reception and greeted me so warmly with genuine kindness and made me feel welcome immediately.
When I met Dr Raquel, she instantly put me at ease. She was caring, inquisitive, attentive and, most importantly, completely honest. After a very thorough assessment, she explained that Botox in my jaw was unlikely to give me the results I was hoping for and that she did not want me to waste my money. I appreciated that honesty so much.
Rather than simply recommending treatments, she took the time to explore everything that could be contributing to both my TMJ symptoms and ageing skin, including my sleep, stress levels, diet, skincare, overall health and lifestyle. I later received a personalised treatment plan, skincare recommendations, advice on supplements and ways to improve my wellbeing from the inside out. I also purchased the supplements and skincare she recommended and have genuinely found them really beneficial.
Over the years I’ve had injectable treatments with several practitioners, but I have never met someone who genuinely cares about their patients as much as Dr Raquel does. Her approach is incredibly holistic and thoughtful, and the results she achieved for me were great but natural, which was very important to me. She truly has an artistic eye for knowing exactly what is enough, not overdone or excessive, just subtle and refreshing enhancements.
I also loved learning more about the regenerative treatments she offers, such as polynucleotides, and I completed a course of treatments with her that I was so happy with. Every visit felt personal and welcoming, more like catching up with an old friend, as Dr Raquel is so warm, genuine and friendly.
Dr Raquel is clearly exceptionally knowledgeable and highly skilled, but what truly sets her apart is the level of care, integrity and passion she brings to every patient experience. I genuinely feel she went above and beyond for me, and I’m so grateful to have found this gem of a clinic.
Natalie, the clinic coordinator, also deserves a special mention. She is incredibly warm, professional and welcoming, and really adds to the whole experience from the moment you arrive. She always checked in with thoughtful WhatsApp messages after my treatments to see how I was feeling, which made the care feel so personal and genuine. Nothing ever felt too much trouble and she helped create such a calm, friendly and luxurious atmosphere throughout every visit.
If you are considering Skin and Medical Cosmetics for the first time, I would say you are in incredibly safe and caring hands. Dr Raquel genuinely wants the best for her patients and takes a thoughtful, honest and holistic approach rather than simply selling treatments. You never feel rushed or pressured and the results are beautifully natural. You are made to feel welcomed, cared for and valued from the moment you walk through the door. I will absolutely be returning and would wholeheartedly recommend Dr Raquel and Skin & Medical Cosmetics to anyone considering aesthetic or skin treatments. Show less »
I initially booked a consultation for concerns around ageing skin and TMJ issues, having heard Botox in the jaw could help. I would quite happily have gone ahead and spent £400 on treatment, so what I received instead was incredibly refreshing and unexpected.
From the moment I walked into the clinic after a busy workday, I instantly felt calm. The clinic itself is beautiful, peaceful, serene, softly lit, with calming music and the loveliest aromatherapy scent throughout. Natalie was on reception and greeted me so warmly with genuine kindness and made me feel welcome immediately.
When I met Dr Raquel, she instantly put me at ease. She was caring, inquisitive, attentive and, most importantly, completely honest. After a very thorough assessment, she explained that Botox in my jaw was unlikely to give me the results I was hoping for and that she did not want me to waste my money. I appreciated that honesty so much.
Rather than simply recommending treatments, she took the time to explore everything that could be contributing to both my TMJ symptoms and ageing skin, including my sleep, stress levels, diet, skincare, overall health and lifestyle. I later received a personalised treatment plan, skincare recommendations, advice on supplements and ways to improve my wellbeing from the inside out. I also purchased the supplements and skincare she recommended and have genuinely found them really beneficial.
Over the years I’ve had injectable treatments with several practitioners, but I have never met someone who genuinely cares about their patients as much as Dr Raquel does. Her approach is incredibly holistic and thoughtful, and the results she achieved for me were great but natural, which was very important to me. She truly has an artistic eye for knowing exactly what is enough, not overdone or excessive, just subtle and refreshing enhancements.
I also loved learning more about the regenerative treatments she offers, such as polynucleotides, and I completed a course of treatments with her that I was so happy with. Every visit felt personal and welcoming, more like catching up with an old friend, as Dr Raquel is so warm, genuine and friendly.
Dr Raquel is clearly exceptionally knowledgeable and highly skilled, but what truly sets her apart is the level of care, integrity and passion she brings to every patient experience. I genuinely feel she went above and beyond for me, and I’m so grateful to have found this gem of a clinic.
Natalie, the clinic coordinator, also deserves a special mention. She is incredibly warm, professional and welcoming, and really adds to the whole experience from the moment you arrive. She always checked in with thoughtful WhatsApp messages after my treatments to see how I was feeling, which made the care feel so personal and genuine. Nothing ever felt too much trouble and she helped create such a calm, friendly and luxurious atmosphere throughout every visit.
If you are considering Skin and Medical Cosmetics for the first time, I would say you are in incredibly safe and caring hands. Dr Raquel genuinely wants the best for her patients and takes a thoughtful, honest and holistic approach rather than simply selling treatments. You never feel rushed or pressured and the results are beautifully natural. You are made to feel welcomed, cared for and valued from the moment you walk through the door. I will absolutely be returning and would wholeheartedly recommend Dr Raquel and Skin & Medical Cosmetics to anyone considering aesthetic or skin treatments. Show less »
Katherine Ryder
Dr. Raquel Skin and Medical Cosmetics18 May 2026 12:12
After significant weight loss, I started to notice some facial volume loss and felt that my face no longer looked quite like “me.” I wanted a very natural result — just a subtle restoration of volume and softness — so I spent a long time researching clinics and doctors in London before booking my consultation.
After following a few pages for aesthetics, I c...
Show more »
After significant weight loss, I started to notice some facial volume loss and felt that my face no longer looked quite like “me.” I wanted a very natural result — just a subtle restoration of volume and softness — so I spent a long time researching clinics and doctors in London before booking my consultation.
After following a few pages for aesthetics, I came across Aesthetic are Clinic with Dr Khaula Safdar on Instagram. I reviewed the procedures that she carried out from the before and after images, and contacted her to discuss my concerns.
The communication from the outset is amazing, even helping with directions to the clinic as I got lost in the maze that is Moorgate 😊
From the very beginning, Dr. Khaula immediately put me at ease. Communication was excellent, she answered every question openly and honestly, and I never once felt rushed or pressured into treatments I didn’t need.
What really stood out was how conservative and thoughtful her approach was. She carefully assessed my face from multiple angles, explained that my concerns were actually less noticeable in person than they appeared in the pictures I had sent through, and reassured me that I only needed a very small amount of filler for a natural result.
The entire process was incredibly professional, calm and safe. She explained every step of the procedure, talked me through aftercare thoroughly, used numbing cream beforehand, and continually checked that I was comfortable throughout.
I especially appreciated how transparent she was about risks, aftercare and what to look out for afterwards, which made me feel genuinely looked after and in very safe hands.
I also really valued that she took time to explain other treatments properly rather than trying to “sell” them. We discussed polynucleotides for the under-eye area and she explained clearly how they work, the science behind them, and when they may be suitable in the future for me. That honesty and depth of knowledge made a huge impression on me.
Definitely be a return customer ❤️ Show less »
After following a few pages for aesthetics, I came across Aesthetic are Clinic with Dr Khaula Safdar on Instagram. I reviewed the procedures that she carried out from the before and after images, and contacted her to discuss my concerns.
The communication from the outset is amazing, even helping with directions to the clinic as I got lost in the maze that is Moorgate 😊
From the very beginning, Dr. Khaula immediately put me at ease. Communication was excellent, she answered every question openly and honestly, and I never once felt rushed or pressured into treatments I didn’t need.
What really stood out was how conservative and thoughtful her approach was. She carefully assessed my face from multiple angles, explained that my concerns were actually less noticeable in person than they appeared in the pictures I had sent through, and reassured me that I only needed a very small amount of filler for a natural result.
The entire process was incredibly professional, calm and safe. She explained every step of the procedure, talked me through aftercare thoroughly, used numbing cream beforehand, and continually checked that I was comfortable throughout.
I especially appreciated how transparent she was about risks, aftercare and what to look out for afterwards, which made me feel genuinely looked after and in very safe hands.
I also really valued that she took time to explain other treatments properly rather than trying to “sell” them. We discussed polynucleotides for the under-eye area and she explained clearly how they work, the science behind them, and when they may be suitable in the future for me. That honesty and depth of knowledge made a huge impression on me.
Definitely be a return customer ❤️ Show less »
Sophie
Aestheticare Clinic13 May 2026 19:07
I’ve had the Aqualyx treatments over a short period of time and have seen miraculous results despite no exercise at all. I can not recommend it enough. Encouraged by the amazing results, I decided to try polynucleotides for under treatment as I have genetic dark circles and compounded with stresses in life, results were beyond my expectations I am glad I tri...
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I’ve had the Aqualyx treatments over a short period of time and have seen miraculous results despite no exercise at all. I can not recommend it enough. Encouraged by the amazing results, I decided to try polynucleotides for under treatment as I have genetic dark circles and compounded with stresses in life, results were beyond my expectations I am glad I tried it because it has transformed me. Iwona makes all the difference as she is professional, very knowledgeable and amazing people skill.
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zoe itu
Lumen Skin Clinic 6 May 2026 15:03
I recently had my lips done along with polynucleotides treatment and I honestly couldn’t be happier with the results. From start to finish, the whole experience was professional, relaxed, and really reassuring. Everything was explained clearly, and I felt completely comfortable throughout.
My lips look natural and exactly what I wanted, and the polynucleoti...
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I recently had my lips done along with polynucleotides treatment and I honestly couldn’t be happier with the results. From start to finish, the whole experience was professional, relaxed, and really reassuring. Everything was explained clearly, and I felt completely comfortable throughout.
My lips look natural and exactly what I wanted, and the polynucleotides have made such a difference to my skin already.
You can really tell how much care and attention goes into Ellie’s work, and the results speak for themselves. I wouldn’t hesitate to recommend to anyone considering treatment — I’ll definitely be coming back! Show less »
My lips look natural and exactly what I wanted, and the polynucleotides have made such a difference to my skin already.
You can really tell how much care and attention goes into Ellie’s work, and the results speak for themselves. I wouldn’t hesitate to recommend to anyone considering treatment — I’ll definitely be coming back! Show less »
Charlotte Luther
Ellie Page Aesthetics 6 May 2026 11:11
Love Ellie and trust her with my face 100% always so professional and ensures I am happy with my results which I definitely always am. You will not be disappointed if you book your treatments with Ellie! I have had Botox, lips and polynucleotide under my eyes
demi Mcdowell
Ellie Page Aesthetics 6 May 2026 10:10
Super impressed ⭐️⭐️⭐️⭐️⭐️
I am quite thorough when choosing an aesthetician ( as you should be ) but I was instantly impressed with Liv’s ethos towards aesthetics, her knowledge when advising how to achieve my desired goal and her care with her clients through all aspects of appointments, treatments and aftercare.
I originally started coming to Liv a...
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Super impressed ⭐️⭐️⭐️⭐️⭐️
I am quite thorough when choosing an aesthetician ( as you should be ) but I was instantly impressed with Liv’s ethos towards aesthetics, her knowledge when advising how to achieve my desired goal and her care with her clients through all aspects of appointments, treatments and aftercare.
I originally started coming to Liv at The Aesthetic Touch for b12 shots and now I’m booking more and more ☺️ I have had Botox and polynucleotide eye treatments so far and have loved the results.
Appointments are always a pleasure and made so easy by Livs friendly attentive nature.
Also Livs investment in the thinnest needles to help clients be as comfortable as possible during treatments is always a green flag.
I would highly recommend Liv and The Aesthetic Touch to anyone and often do ☺️
With free parking being so close it also makes visits super easy. Show less »
I am quite thorough when choosing an aesthetician ( as you should be ) but I was instantly impressed with Liv’s ethos towards aesthetics, her knowledge when advising how to achieve my desired goal and her care with her clients through all aspects of appointments, treatments and aftercare.
I originally started coming to Liv at The Aesthetic Touch for b12 shots and now I’m booking more and more ☺️ I have had Botox and polynucleotide eye treatments so far and have loved the results.
Appointments are always a pleasure and made so easy by Livs friendly attentive nature.
Also Livs investment in the thinnest needles to help clients be as comfortable as possible during treatments is always a green flag.
I would highly recommend Liv and The Aesthetic Touch to anyone and often do ☺️
With free parking being so close it also makes visits super easy. Show less »
Miichaela McCarthy
The Aesthetic Touch 3 May 2026 21:09
I’ve been coming to Efface for over 4 years now. They do such an amazing job. looking back at photos over the past 4 years I look much younger now.
I do get quite nervous about procedures but Michelle explains everything well and puts me at ease
I wouldn’t go anywhere else
I’ve had Botox, polynucleotides, Profhilo and filler and all have made a massive impa...
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I’ve been coming to Efface for over 4 years now. They do such an amazing job. looking back at photos over the past 4 years I look much younger now.
I do get quite nervous about procedures but Michelle explains everything well and puts me at ease
I wouldn’t go anywhere else
I’ve had Botox, polynucleotides, Profhilo and filler and all have made a massive impact.
I feel so much more confident. Show less »
I do get quite nervous about procedures but Michelle explains everything well and puts me at ease
I wouldn’t go anywhere else
I’ve had Botox, polynucleotides, Profhilo and filler and all have made a massive impact.
I feel so much more confident. Show less »
Anna Clayton
Efface Aesthetics 2 May 2026 15:03
Dr Trish is professional, and has a great wealth of knowledge of aesthetics and skincare. I’ve been undergoing microneedling and polynucleotides for under eyes, and have seen an improvement in my skin quality after a couple of treatments.
Saba Mariam Sajid
Rebalance Your Life Positive Ageing Clinic27 April 2026 17:05
I had polynucleotide eye treatment at MA Medical with Victoria, and I couldn’t be happier with my experience. From the moment I arrived, the clinic felt professional, clean, and welcoming.
Victoria was fantastic—she took the time to explain the treatment in detail and made me feel completely at ease. Her approach was calm, knowledgeable, and very reassuring...
Show more »
I had polynucleotide eye treatment at MA Medical with Victoria, and I couldn’t be happier with my experience. From the moment I arrived, the clinic felt professional, clean, and welcoming.
Victoria was fantastic—she took the time to explain the treatment in detail and made me feel completely at ease. Her approach was calm, knowledgeable, and very reassuring.
The treatment itself was carried out with great care and precision. I felt I was in very safe hands throughout.
I’m already looking forward to seeing the full results and wouldn’t hesitate to return or recommend MA Medical to others considering similar treatments. Show less »
Victoria was fantastic—she took the time to explain the treatment in detail and made me feel completely at ease. Her approach was calm, knowledgeable, and very reassuring.
The treatment itself was carried out with great care and precision. I felt I was in very safe hands throughout.
I’m already looking forward to seeing the full results and wouldn’t hesitate to return or recommend MA Medical to others considering similar treatments. Show less »
Michelle De ste croix
MA Medical23 April 2026 14:02
I had an appointment with Jayne for polynucleotides under my eyes. This was my first time ever having any sort of aesthetic treatment.
Jayne is so informative and explains everything.
I was expecting the procedure to be have some pain involved and as an anxious person in general, I really was surprised.
Jayne made me feel so comfortable and she was so gentle...
Show more »
I had an appointment with Jayne for polynucleotides under my eyes. This was my first time ever having any sort of aesthetic treatment.
Jayne is so informative and explains everything.
I was expecting the procedure to be have some pain involved and as an anxious person in general, I really was surprised.
Jayne made me feel so comfortable and she was so gentle when doing it, I hardly felt a thing.
I am so pleased, I felt totally in safe hands and look forward to going back to Jayne for my next treatment . Show less »
Jayne is so informative and explains everything.
I was expecting the procedure to be have some pain involved and as an anxious person in general, I really was surprised.
Jayne made me feel so comfortable and she was so gentle when doing it, I hardly felt a thing.
I am so pleased, I felt totally in safe hands and look forward to going back to Jayne for my next treatment . Show less »
Caroline Mckeown
Fresh Aesthetics & Skin - Botox, fillers, lip fillers, skincare22 April 2026 17:05
I've been getting polynucleotide treatment around my eyes for 3 years at Solihull Aesthetics, and I recommend it to anyone who, like me, has dark circles.
Hannah is kind and friendly, she is a professional through and through, I trust her and her judgment. Her husband, who works with her, is lovely and very kind. I'm so glad for your success. Thank you!
Hannah is kind and friendly, she is a professional through and through, I trust her and her judgment. Her husband, who works with her, is lovely and very kind. I'm so glad for your success. Thank you!
Carmen Hurtado
Solihull Aesthetics22 April 2026 17:05
What can I say but Dr Don is a genius. I really needed to find someone who was not only good at doing treatments, but someone who came across as he actually cared about his work, and makes you feel really comfortable in the process.
Had a few treatments now with Dr Don and must say he really is amazing at what he does. I’m feeling faboulous. I would also...
Show more »
What can I say but Dr Don is a genius. I really needed to find someone who was not only good at doing treatments, but someone who came across as he actually cared about his work, and makes you feel really comfortable in the process.
Had a few treatments now with Dr Don and must say he really is amazing at what he does. I’m feeling faboulous. I would also like to mention the really lovely Natalie who takes all my calls with such enthusiasm and professionalism. I really feel he cares in what he does, and it’s about self confident and he gives me bundles. I really recommend him for all your treatments as he’s great.
Can’t wait for my next polynucleotide treatment and feeling cofident again in my skin. Show less »
Had a few treatments now with Dr Don and must say he really is amazing at what he does. I’m feeling faboulous. I would also like to mention the really lovely Natalie who takes all my calls with such enthusiasm and professionalism. I really feel he cares in what he does, and it’s about self confident and he gives me bundles. I really recommend him for all your treatments as he’s great.
Can’t wait for my next polynucleotide treatment and feeling cofident again in my skin. Show less »
15 April 2026 19:07
I’ve been going to Sian for years for various treatments, and I genuinely wouldn’t trust anyone else. She’s incredibly knowledgeable, always takes the time to talk you through every step, and makes you feel completely at ease. I highly recommend polynucleotides—they’ve made such a noticeable difference to the overall appearance of my skin. She really is the...
Show more »
I’ve been going to Sian for years for various treatments, and I genuinely wouldn’t trust anyone else. She’s incredibly knowledgeable, always takes the time to talk you through every step, and makes you feel completely at ease. I highly recommend polynucleotides—they’ve made such a noticeable difference to the overall appearance of my skin. She really is the best!
Show less »
Faye Keegan
Pure Aesthetics By Sian14 April 2026 20:08
I recently had a polynucleotide eye treatment and had a really positive experience. I’m quite scared of needles, but Saida made me feel so comfortable and at ease throughout the whole process.
The treatment itself was quick, with minimal downtime, and I’ve already noticed my under-eye area looking more hydrated and refreshed. Definitely recommend if you’re...
Show more »
I recently had a polynucleotide eye treatment and had a really positive experience. I’m quite scared of needles, but Saida made me feel so comfortable and at ease throughout the whole process.
The treatment itself was quick, with minimal downtime, and I’ve already noticed my under-eye area looking more hydrated and refreshed. Definitely recommend if you’re considering something subtle and natural-looking! Show less »
The treatment itself was quick, with minimal downtime, and I’ve already noticed my under-eye area looking more hydrated and refreshed. Definitely recommend if you’re considering something subtle and natural-looking! Show less »
Aisha Chaudhry
KAST Medical Aesthetics14 April 2026 17:05
A genuinely five-star experience from start to finish.
From the moment I arrived at the Vie Clinic, I felt welcomed and completely looked after. My treatment was with Dr Olga Andriyuk and she was exceptional. I explained my concerns, and she took her time to really understand what I wanted before recommending the best approach, nothing felt rushed, everythi...
Show more »
A genuinely five-star experience from start to finish.
From the moment I arrived at the Vie Clinic, I felt welcomed and completely looked after. My treatment was with Dr Olga Andriyuk and she was exceptional. I explained my concerns, and she took her time to really understand what I wanted before recommending the best approach, nothing felt rushed, everything felt considered.
She explained every step so clearly, which instantly put me at ease. I was a little nervous, but she was so gentle, calm, and reassuring throughout the treatment.
I had under-eye polynucleotides, Botox and a nose treatment which I had seen advertised on their Instagram page with fabulous results, already after just three days I can see a difference.
What stood out most was how thorough and caring she was, including the aftercare advice, it really felt like a premium, thoughtful experience.
I wouldn’t hesitate to recommend, I felt completely safe in her hands. Show less »
From the moment I arrived at the Vie Clinic, I felt welcomed and completely looked after. My treatment was with Dr Olga Andriyuk and she was exceptional. I explained my concerns, and she took her time to really understand what I wanted before recommending the best approach, nothing felt rushed, everything felt considered.
She explained every step so clearly, which instantly put me at ease. I was a little nervous, but she was so gentle, calm, and reassuring throughout the treatment.
I had under-eye polynucleotides, Botox and a nose treatment which I had seen advertised on their Instagram page with fabulous results, already after just three days I can see a difference.
What stood out most was how thorough and caring she was, including the aftercare advice, it really felt like a premium, thoughtful experience.
I wouldn’t hesitate to recommend, I felt completely safe in her hands. Show less »
13 April 2026 19:07
FAQ
Is the treatment painful?
The injections may be slightly sensitive, but a numbing cream is usually applied to make the procedure comfortable.
How long do the results last?
The effects usually last 6 to 12 months, depending on your skin type and lifestyle.
Are there any risks?
The treatment is generally safe. Redness, swelling, or bruising usually disappears within a few days.
What does a treatment cost?
The costs vary per clinic, but are often between £260 and £520 per session.
Which clinics in the United Kingdom offer this treatment?
On Injectablesbooking, you can easily find clinics that offer this treatment. The platform provides an overview of recognised clinics and GMC-registered doctors. Compare clinics based on experience, prices, and reviews to make the best choice.
Compare clinics in London
Promoted
Top rated
4.8
(194 reviews)
London, West End Lane 269
7 km
- Botox zone from
- £ 180,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 300,00
Promoted
Top rated
4.9
(218 reviews)
London, Dover Street 15
1 km
- Botox zone from
- £ 300,00
- Filler per ml from
- £ 350,00
- Profhilo per 2 ml from
- £ 350,00
Promoted
Top rated
4.6
(4020 reviews)
London, Wigmore Street
2 km
- Botox zone from
- £ 129,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 195,00
Promoted
Top rated
4.6
(2767 reviews)
London
6 km
- Botox zone from
- £ 129,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 195,00
Promoted
Top rated
4.6
(2473 reviews)
London, Cabot Square 1
7 km
- Botox zone from
- £ 129,00
- Filler per ml from
- £ 250,00
- Profhilo per 2 ml from
- £ 195,00
London, Pall Mall 120
<1 km
- Botox zone from
- £ 200,00
- Filler per ml from
- -
- Profhilo per 2 ml from
- £ 300,00
London, St James's Street 20
<1 km
- Botox zone from
- £ 230,00
- Filler per ml from
- £ 380,00
- Profhilo per 2 ml from
- £ 280,00
4.8
(133 reviews)
London, Wardour Street 89-91
<1 km
- Botox zone from
- £ 300,00
- Filler per ml from
- £ 350,00
- Profhilo per 2 ml from
- -
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