Profhilo side effects are usually mild and temporary. Many people notice small lumps, redness or mild swelling immediately after treatment, particularly during the first 24 hours.

Profhilo contains stabilised hyaluronic acid and is used to improve skin hydration, elasticity and overall skin quality. Because it spreads beneath the skin, recovery can differ slightly from traditional dermal fillers.

Common reactions may occur due to:

  • The injections themselves

  • Temporary fluid retention

  • The skin's natural inflammatory response

Profhilo is commonly chosen for:

  • Mild skin laxity

  • Fine lines

  • Dehydrated skin

  • Early signs of collagen loss

See also:
Profhilo treatment

What are the most common Profhilo side effects?

The most commonly reported side effects include:

  • Redness

  • Swelling

  • Small lumps at injection sites

  • Bruising

  • Skin tenderness

  • Mild itching

These reactions are generally temporary and often settle within a few hours to several days.

Side effects and recovery

Side effect

Typical recovery

Redness

Several hours to 1 day

Swelling

1–2 days

Small lumps

12–24 hours

Bruising

Several days

Tenderness

1–3 days

Mild itching

Usually short-lived

Contact your practitioner if symptoms worsen, become painful or persist longer than expected.

Lumps after Profhilo

Small lumps after Profhilo are usually normal. They occur because the product is placed at specific injection points and gradually spreads beneath the skin.

Visibility can depend on:

  • Skin thickness

  • Treatment area

  • Fluid retention

  • Injection depth

Unless advised by your practitioner, avoid massaging the treated area.

Results vary between individuals. Viewing before-and-after photos can help set realistic expectations.

How long does swelling last after Profhilo?

Swelling is usually caused by:

  • The injection process

  • Temporary water retention from hyaluronic acid

  • The skin's normal healing response

Most swelling is mild and improves noticeably within 1 to 2 days. In some people, especially in delicate treatment areas, minor swelling may last slightly longer.

Bruising after Profhilo

Bruising can occur if a small blood vessel is affected during treatment.

The likelihood may increase with:

  • Blood-thinning medication

  • Alcohol consumption

  • Smoking

  • Intense exercise before treatment

Bruising generally fades naturally over several days.

Recovery timeline

Timeframe

What is usually normal

Immediately after treatment

Small lumps and redness

First 24 hours

Mild swelling

2–5 days

Bruising improves

1–2 weeks

Skin appears calmer and more even

Recovery after a Profhilo treatment

Most people return to normal daily activities shortly after treatment.

For the first 24 to 48 hours, practitioners commonly advise avoiding:

  • Intense exercise

  • Saunas and excessive heat

  • Alcohol

  • Touching injection sites

  • Prolonged direct sun exposure

  • Aggressive skin treatments

A cool compress may help reduce temporary swelling.

When should you contact a medical professional?

Serious complications are uncommon, but medical assessment may be needed if you experience:

  • Increasing pain

  • Significant swelling

  • Uneven swelling

  • Hot or increasingly red skin

  • Pus or discharge

  • Firm painful nodules

  • Breathing difficulties or signs of an allergic reaction

A qualified practitioner can determine whether symptoms are part of normal recovery or require treatment.

Cosmetic specialists in United Kingdom

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Arun Karwal
Dr. Arun Karwal
Profession
Aesthetic Doctor
Profhilo from
£ 350,00
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Yvonne Ndefo
Dr. Yvonne Ndefo
Profession
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£ 259,00
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Zara Katchi
Dr. Zara Katchi
Profession
Aesthetic Doctor
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£ 259,00
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Jade Hill
BSc. Jade Hill
Profession
Nurse prescriber (V300 Independent)
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£ 227,00
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Monaf Al-Samawi
Dr. Monaf Al-Samawi
Profession
Medical Doctor
Profhilo from
£ 325,00
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Tanya Vyland
Dr. Tanya Vyland
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Natalie Gladstone
Natalie Gladstone

Profhilo vs fillers: side effects

Although both contain hyaluronic acid, they work differently.

Profhilo

Dermal fillers

Focus on skin quality

Focus on volume and contour

Spreads beneath the skin

Remains more localised

Minimal contour change

Greater volume effect

Temporary swelling common

More visible product placement possible

Recovery and side effects can therefore differ between treatments.

What is the difference between Profhilo and skin boosters?

Both treatments aim to improve hydration and skin quality, but there are differences.

  • Profhilo spreads more broadly beneath the skin

  • Skin boosters are often placed more superficially

  • Skin boosters primarily focus on hydration

  • Profhilo may also support collagen and elastin production

Recovery experiences can vary depending on the treatment used.

Factors that may increase bruising

Factor

Increased likelihood

Alcohol

Yes

Blood-thinning medication

Yes

Intense exercise

Yes

Sensitive skin

Yes

Reducing the risk of Profhilo complications

Choosing an experienced practitioner can help reduce the likelihood of complications.

You can also help minimise risks by:

  • Attending a medical consultation

  • Discussing medications beforehand

  • Following aftercare instructions carefully

  • Choosing a reputable clinic

See also:
Profhilo reviews

Reviews of Profhilo in the UK

Profhilo love the results Emma explains the procedure from the outset. Takes her time no rushing. Very professional I am always really happy with the results. Highly recommend Emma ❤️
Samantha Stables
Aurora Beauty Aesthetics
9 March 2026 03:03
A brilliant experience as always, loving the new consulting room🕶️ Dr Cei explains the process clearly, always listening to what I want to achieve, and reminding me to ‘trust the process’ I can now clearly see the results of the Profhilo Structura and am very pleased 😍 Next procedure booked 👍 I would highly recommend Dr Cei she is amazing!
suzzanne whiting
Dr Cei Aesthetics
5 March 2026 17:05
I honestly wouldn’t trust anyone else with my aesthetics. Natalie and the girls are absolutely amazing. I’ve been going to them for my Botox, skin pen, Profhilo and Morpheus treatments and the care they give every single time is incredible. Natalie is so knowledgeable, patient and genuinely lovely. She always takes the time to talk everything through proper... Show more »
I honestly wouldn’t trust anyone else with my aesthetics. Natalie and the girls are absolutely amazing. I’ve been going to them for my Botox, skin pen, Profhilo and Morpheus treatments and the care they give every single time is incredible.

Natalie is so knowledgeable, patient and genuinely lovely. She always takes the time to talk everything through properly and makes sure you feel completely comfortable before doing anything. You never feel rushed and she really listens to what you want, which makes such a difference.

The whole team are so kind and welcoming and they always make you feel at ease. For me, it’s about trust and I completely trust them with my face. The results are always natural and exactly what I’m looking for.

I wouldn’t go anywhere else Show less »
Caroline Stephanie Young
Naturally Flawless Aesthetics
5 March 2026 14:02
I recently visited Kate Bell Aesthetics for a HydroFacial with Emma and a Profhilo skin booster treatment with Kate, and the experience was fantastic from start to finish. Emma’s HydroFacial was both relaxing and incredibly thorough – my skin looked brighter, clearer and felt deeply hydrated afterwards. Kate is exceptionally knowledgeable and her clinical ba... Show more »
I recently visited Kate Bell Aesthetics for a HydroFacial with Emma and a Profhilo skin booster treatment with Kate, and the experience was fantastic from start to finish. Emma’s HydroFacial was both relaxing and incredibly thorough – my skin looked brighter, clearer and felt deeply hydrated afterwards. Kate is exceptionally knowledgeable and her clinical background as a nurse practitioner is very reassuring, but she is also warm, personable and genuinely interested in helping clients achieve natural, confidence-boosting results. My Profhilo treatment was carefully explained and I felt completely at ease throughout. The whole team at Kate Bell Aesthetics creates such a calm, professional environment. If you’re considering aesthetic treatments but feel nervous about booking, this clinic is the perfect place to start. Highly recommend. Show less »
5 March 2026 10:10
I have a course of 4 Neogen plasma booked and so far I have had two of those sessions. Six days after my first session I bumped into a friend who commented how amazing my skin looked 😊. I can't wait to see the results continue to develop over the coming months. If you are looking for complete skin rejuvenation then seeing Amrita is for you. The clinic is al... Show more »
I have a course of 4 Neogen plasma booked and so far I have had two of those sessions. Six days after my first session I bumped into a friend who commented how amazing my skin looked 😊. I can't wait to see the results continue to develop over the coming months. If you are looking for complete skin rejuvenation then seeing Amrita is for you. The clinic is also such a lovely calm space. Show less »
I can’t recommend Amrita highly enough! I’ve been going to her for the last couple of years and she is absolutely fantastic. She is incredibly knowledgeable, professional and makes you feel completely comfortable and confident in her hands. Being a former dentist gives me total reassurance when it comes to treatments and injections. I’ve had both Botox and P... Show more »
I can’t recommend Amrita highly enough! I’ve been going to her for the last couple of years and she is absolutely fantastic. She is incredibly knowledgeable, professional and makes you feel completely comfortable and confident in her hands.
Being a former dentist gives me total reassurance when it comes to treatments and injections. I’ve had both Botox and Profhilo with her and the results have always been amazing natural, fresh and exactly what I wanted.
She takes the time to explain everything and always advises what will work best for you to achieve the best possible results. I always leave feeling so much more confident and can’t wait for my next treatments. Show less »
4 March 2026 13:01

Compare Profhilo clinics

If you are considering Profhilo treatment, compare clinics, practitioner experience, patient reviews and available treatment information before making a decision.

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Compare clinics in United Kingdom

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Hampstead Aesthetics
Hampstead Aesthetics
London, West End Lane 269
Profhilo from
£ 300,00
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Karwal Aesthetics
Karwal Aesthetics
London, Dover Street 15
Profhilo from
£ 350,00
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Thérapie Clinic - Birmingham City Centre
Thérapie Clinic - Birmingham City Centre
Birmingham, Lower Temple Street
Profhilo from
£ 259,00
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Thérapie Clinic - Liverpool
Thérapie Clinic - Liverpool
Liverpool, South John Street 46a
Profhilo from
£ 259,00
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Thérapie Clinic - Bath
Thérapie Clinic - Bath
Bath, Southgate Place 12
Profhilo from
£ 259,00
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Thérapie Clinic - Belfast
Thérapie Clinic - Belfast
Belfast, Ann Street 36
Profhilo from
£ 259,00
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Thérapie Clinic - Bluewater, Kent
Thérapie Clinic - Bluewater, Kent
Greenhithe
Profhilo from
£ 259,00
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Thérapie Clinic - Brighton and Hove
Thérapie Clinic - Brighton and Hove
Hove, Western Road 98
Profhilo from
£ 259,00
View profile

Frequently asked questions about Profhilo

How long do Profhilo side effects last?

Are lumps after Profhilo normal?

Is Profhilo safe?

Can you have an allergic reaction to Profhilo?

What should I avoid after Profhilo?

How long does swelling last after Profhilo?

Can I wear make-up after Profhilo?

What is the difference between Profhilo and fillers?

Can Profhilo be combined with fillers or anti-wrinkle injections?

Can I exercise after Profhilo?

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