Does Profhilo hurt?

Profhilo is an innovative skin treatment that enhances hydration and rejuvenation by using highly concentrated hyaluronic acid. It’s a popular choice for those who want to address the signs of skin ageing without resorting to more invasive procedures. One of the most common questions about this treatment is: “Does Profhilo hurt?” In this article, we’ll explain what you can expect and how most people describe the sensation during treatment.

What is Profhilo?

Profhilo is a treatment in which hyaluronic acid is injected deep into the skin to improve hydration and strengthen the skin’s structure. What makes this treatment unique is its exceptionally high concentration of pure hyaluronic acid (62 mg per 2 ml syringe), providing intense hydration and improving skin elasticity, firmness, and overall tone.

Unlike dermal fillers or Botox, which mainly focus on adding volume or relaxing facial muscles, Profhilo works to enhance the overall quality of the skin. It’s ideal for those who want to address the first signs of skin ageing without undergoing more invasive cosmetic procedures.

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Does a Profhilo treatment hurt?

It’s a common question does Profhilo hurt? The answer largely depends on your personal pain threshold, but most people describe the treatment as slightly uncomfortable rather than painful.

The procedure typically involves 10 small injections: 5 on each side of the face, in areas such as in front of the ear, along the cheeks, near the jawline, and below the lower lip. Each injection only takes a few seconds, although you might feel a mild stinging or tingling sensation as the product is injected into the skin.

While the needle used is very fine, the hyaluronic acid can sometimes cause a brief burning or tightening feeling during injection. This usually subsides quickly once the treatment is complete.

Many clinics choose not to apply numbing cream, as this can occasionally increase the risk of bruising. However, distraction techniques are often used instead — for example, holding a stress ball or using a gentle vibrating device on the skin to make the experience more comfortable.

What can you expect during and after the treatment?

The Profhilo treatment is quick and efficient, and consists of the following steps:

  1. Consultation: During your first appointment, you’ll discuss with your practitioner whether Profhilo is suitable for your skin type and goals. Photos of the treatment area are usually taken, and you’ll be asked to sign a consent form.

  2. The injections: The treatment itself only takes a few minutes. You’ll receive 10 small injections (5 on each side of the face), with each injection lasting just a few seconds.

  3. After the treatment: It’s normal to experience mild redness, swelling, or small bumps at the injection sites. These usually settle quite quickly. After your appointment, it’s recommended to avoid touching the treated areas or applying makeup for around 12 hours. You should also avoid intense exercise and alcohol for the first 48 hours.

Is Profhilo painful enough to stop you from having the treatment?

While the treatment can cause some mild discomfort, it’s generally not painful enough to put people off having Profhilo again. The procedure is quick, and the results are natural and effective. Most patients find that the benefits of the treatment far outweigh any temporary discomfort.

If you’re concerned about pain, don’t hesitate to ask your practitioner about ways to make the treatment more comfortable. This may include distraction techniques or, if available, the use of a numbing cream.

This is my second review of Diyah Aesthetic clinic. I'd like to correct my previous negative comments due to a misunderstanding. I had my Profhilo treatment today, and it was more than satisfactory. Both the clinic and the injector exude a calming atmosphere, she was very polite, and the treatment was painless. I will be returning for a second session. Thank... Show more »
This is my second review of Diyah Aesthetic clinic. I'd like to correct my previous negative comments due to a misunderstanding. I had my Profhilo treatment today, and it was more than satisfactory. Both the clinic and the injector exude a calming atmosphere, she was very polite, and the treatment was painless. I will be returning for a second session. Thank you. Show less »
16 June 2026 16:04
I’ve had quite a few treatments here and I am a regular (can’t stop coming!) 😁 Treatments I have had include; The Exilis Ultra 360 Emsculpt & Hi EMT (Emsculpt was soo good!) Profhilo Lemon Bottle & Aqualyx (I preferred Aqualyx of the two) Botox I have regularly and I am always pleased with the results. It’s always nice seeing the girls and I always enjoy... Show more »
I’ve had quite a few treatments here and I am a regular (can’t stop coming!) 😁

Treatments I have had include;
The Exilis Ultra 360
Emsculpt & Hi EMT (Emsculpt was soo good!)
Profhilo
Lemon Bottle & Aqualyx (I preferred Aqualyx of the two)
Botox I have regularly and I am always pleased with the results.

It’s always nice seeing the girls and I always enjoy my visits here. I fully recommend. I usually have Laura is really nice, gentle, understandong and highly professional.

Thank again for all my treatments so far! 😊 Show less »
Fjoralba Hysko
Serene Skin & Beauty
7 June 2026 13:01
I recently had Profhilo treatment at this clinic and honestly had such a great experience from start to finish. Emel is professional, welcoming, and made me feel completely comfortable throughout the whole appointment. Everything was explained clearly, including the procedure and aftercare. The clinic itself was spotless. The treatment was quick and handled... Show more »
I recently had Profhilo treatment at this clinic and honestly had such a great experience from start to finish. Emel is professional, welcoming, and made me feel completely comfortable throughout the whole appointment.
Everything was explained clearly, including the procedure and aftercare.
The clinic itself was spotless. The treatment was quick and handled so gently, and I'm already noticing my skin looking more hydrated, smoother, and glowing naturally.
I'm so happy with the results and will definitely be returning for future treatments. Highly recommend this clinic to anyone.
Thank you 🙏 Show less »
Valentina Lazarovska
AesClinica London
28 May 2026 16:04
I got Botox and Profhilo done and I love the results so far, it's only been a week. I will be back. 100% recommend. Fast service and she answers all questions.
Zoraida Lopez
Brighton Beauty Bar
23 May 2026 11:11
I want to say I've been coming to Enhance Clinispa for about 4 years. The clinic is absolutely gorgeous and the staff are very friendly and helpful. I was unfortunately late for an appointment due to traffic and they were so understanding. I have Botox and Profhilo and use the ZO skincare. Fab and Nic are so helpful with their advice and always recommend wh... Show more »
I want to say I've been coming to Enhance Clinispa for about 4 years. The clinic is absolutely gorgeous and the staff are very friendly and helpful. I was unfortunately late for an appointment due to traffic and they were so understanding.

I have Botox and Profhilo and use the ZO skincare. Fab and Nic are so helpful with their advice and always recommend what is best for me, they never upsell anything I don't need. They always do what is best for the client.

I am renewing my wedding vows in 2weeks and I wanted to feel confident on the photos. I feel this has been accomplished thanks to these two!

Also a little Aperol Spritz and and a good chat in the clinic, I didn't want to leave!

I found this clinic after going elsewhere and the comparison from there to Enhance is second to none! They are top draw with every aspect of the client experience and I now bring my family members. We travel a 2 hour round trip and worth it! Show less »
22 May 2026 14:02
New and definitely returning client, lovely clinic and Kirsty was fabulous and professional, I had lip augmentation which I absolutely love, she explained the process and different ways we can do this very clearly, she listened and delivered! I also had my first round of profhilo, I’m so excited to see the results and I’m glad I’ve started my skin care journ... Show more »
New and definitely returning client, lovely clinic and Kirsty was fabulous and professional, I had lip augmentation which I absolutely love, she explained the process and different ways we can do this very clearly, she listened and delivered!
I also had my first round of profhilo,
I’m so excited to see the results and I’m glad I’ve started my skin care journey here. Oh, Kirsty agave me a sample of her own brand serum, I used it last night and I can see the difference, amazing! Definitely purchasing one next time. Thank you x Show less »
15 May 2026 06:06
I’m a new client to Dr Susie and I am more than thrilled with my treatments. I have had Botox for many years and wanted to make sure I was in safe professional hands which I was. Profhilo was totally new to me but now I’ve just had my second treatment the results, I think, are more than I had hoped for. My skin feels plumper and hydrated with a more glowy co... Show more »
I’m a new client to Dr Susie and I am more than thrilled with my treatments. I have had Botox for many years and wanted to make sure I was in safe professional hands which I was. Profhilo was totally new to me but now I’ve just had my second treatment the results, I think, are more than I had hoped for. My skin feels plumper and hydrated with a more glowy complexion, so together with a little Botox I feel great! The clinic setting is beautiful and easy to access - definitely 5 stars and thank you Susie you are great! Show less »
8 May 2026 07:07
I’ve been coming to Efface for over 4 years now. They do such an amazing job. looking back at photos over the past 4 years I look much younger now. I do get quite nervous about procedures but Michelle explains everything well and puts me at ease I wouldn’t go anywhere else I’ve had Botox, polynucleotides, Profhilo and filler and all have made a massive impa... Show more »
I’ve been coming to Efface for over 4 years now. They do such an amazing job. looking back at photos over the past 4 years I look much younger now.
I do get quite nervous about procedures but Michelle explains everything well and puts me at ease
I wouldn’t go anywhere else
I’ve had Botox, polynucleotides, Profhilo and filler and all have made a massive impact.
I feel so much more confident. Show less »
Anna Clayton
Efface Aesthetics
2 May 2026 15:03
I am so impressed with Dr Yiannis at The Anti Wrinkle Clinic. He struck the perfect balance of being highly professional while also warm and approachable. He listened carefully to my concerns, took time to understand what I was comfortable with (and what I wasn’t), and talked me through all the options without any pressure to proceed. I’m incredibly impress... Show more »
I am so impressed with Dr Yiannis at The Anti Wrinkle Clinic. He struck the perfect balance of being highly professional while also warm and approachable. He listened carefully to my concerns, took time to understand what I was comfortable with (and what I wasn’t), and talked me through all the options without any pressure to proceed.

I’m incredibly impressed with the results from my Botox and Profhilo treatments. I still look like myself—just a fresher, more refined version. It genuinely feels like I’m looking at the same person in the mirror, but at her best. The biggest difference is how I feel: more confident and no longer worried about ageing in the same way.

Thank you, Dr Yiannis, for such a thoughtful approach and for helping me look and feel my best.

Claire Show less »
30 April 2026 09:09
I’ve now had both my first and second Profhilo sessions, and I can honestly say I’m really pleased with the results so far. I started noticing a subtle difference after the first treatment, but after the second session my skin looks fresher, smoother, and more hydrated. What I love most is how natural it looks — it’s not overdone at all, just a healthier, m... Show more »
I’ve now had both my first and second Profhilo sessions, and I can honestly say I’m really pleased with the results so far. I started noticing a subtle difference after the first treatment, but after the second session my skin looks fresher, smoother, and more hydrated.

What I love most is how natural it looks — it’s not overdone at all, just a healthier, more youthful glow. The whole experience has been professional and reassuring from start to finish, which made me feel completely comfortable.

I’d definitely recommend this treatment to anyone wanting a subtle but noticeable improvement in their skin. I’m really happy I went ahead with it Show less »
25 April 2026 09:09
Just had my second profhilo with Carey. Really pleased. Have booked in for some fillers in another free weeks. Hope I don’t get addicted to these procedures it’s nice to tamper yourself. Thanks Carey
Virginia Ridpath
Venom Aesthetics
11 April 2026 19:07
⭐⭐⭐⭐⭐ I had Botox and Profhilo with Yulia and I couldn’t be happier with the results. Yulia is so experienced and professional. She took plenty of time to really listen to what I wanted, answered all my questions, and made me feel completely at ease. The treatment itself was excellent — my face now looks noticeably fresher, smoother, and more youthful w... Show more »
⭐⭐⭐⭐⭐
I had Botox and Profhilo with Yulia and I couldn’t be happier with the results. Yulia is so experienced and professional. She took plenty of time to really listen to what I wanted, answered all my questions, and made me feel completely at ease.
The treatment itself was excellent — my face now looks noticeably fresher, smoother, and more youthful while still looking completely natural. I’ve had so many compliments!
I highly recommend Yulia if you’re looking for beautiful, subtle results from someone who truly cares about what you want. Thank you so much! Show less »
Tatiana Collinge
SHÈ aesthetics
11 April 2026 14:02

Does Profhilo hurt?

Profhilo generally causes only minor discomfort during the treatment, which most people do not find unbearable. The sensation is often described as a slight tingling or prickling, which quickly subsides after the injections. Thanks to the fine needles and distraction techniques, the procedure is well tolerated.

Curious about Profhilo or want to book a treatment? Compare clinics on Injectablesbooking.co.uk, read reviews from other clients, and find the best prices and practitioners near you.

With Profhilo, you get an effective and quick way to improve your skin’s health without needing an invasive procedure.

Frequently asked questions about Profhilo treatment

Is a Profhilo treatment painful?

What do you see after Profhilo?

What are you not allowed to do after Profhilo?

Can Profhilo fail?

Why not Profhilo in forehead?

How long should bumps remain after Profhilo?

What is better, Profhilo or Botox?

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