Does Profhilo hurt?

Profhilo is an innovative skin treatment that enhances hydration and rejuvenation by using highly concentrated hyaluronic acid. It’s a popular choice for those who want to address the signs of skin ageing without resorting to more invasive procedures. One of the most common questions about this treatment is: “Does Profhilo hurt?” In this article, we’ll explain what you can expect and how most people describe the sensation during treatment.

What is Profhilo?

Profhilo is a treatment in which hyaluronic acid is injected deep into the skin to improve hydration and strengthen the skin’s structure. What makes this treatment unique is its exceptionally high concentration of pure hyaluronic acid (62 mg per 2 ml syringe), providing intense hydration and improving skin elasticity, firmness, and overall tone.

Unlike dermal fillers or Botox, which mainly focus on adding volume or relaxing facial muscles, Profhilo works to enhance the overall quality of the skin. It’s ideal for those who want to address the first signs of skin ageing without undergoing more invasive cosmetic procedures.

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Does a Profhilo treatment hurt?

It’s a common question does Profhilo hurt? The answer largely depends on your personal pain threshold, but most people describe the treatment as slightly uncomfortable rather than painful.

The procedure typically involves 10 small injections: 5 on each side of the face, in areas such as in front of the ear, along the cheeks, near the jawline, and below the lower lip. Each injection only takes a few seconds, although you might feel a mild stinging or tingling sensation as the product is injected into the skin.

While the needle used is very fine, the hyaluronic acid can sometimes cause a brief burning or tightening feeling during injection. This usually subsides quickly once the treatment is complete.

Many clinics choose not to apply numbing cream, as this can occasionally increase the risk of bruising. However, distraction techniques are often used instead — for example, holding a stress ball or using a gentle vibrating device on the skin to make the experience more comfortable.

What can you expect during and after the treatment?

The Profhilo treatment is quick and efficient, and consists of the following steps:

  1. Consultation: During your first appointment, you’ll discuss with your practitioner whether Profhilo is suitable for your skin type and goals. Photos of the treatment area are usually taken, and you’ll be asked to sign a consent form.

  2. The injections: The treatment itself only takes a few minutes. You’ll receive 10 small injections (5 on each side of the face), with each injection lasting just a few seconds.

  3. After the treatment: It’s normal to experience mild redness, swelling, or small bumps at the injection sites. These usually settle quite quickly. After your appointment, it’s recommended to avoid touching the treated areas or applying makeup for around 12 hours. You should also avoid intense exercise and alcohol for the first 48 hours.

Is Profhilo painful enough to stop you from having the treatment?

While the treatment can cause some mild discomfort, it’s generally not painful enough to put people off having Profhilo again. The procedure is quick, and the results are natural and effective. Most patients find that the benefits of the treatment far outweigh any temporary discomfort.

If you’re concerned about pain, don’t hesitate to ask your practitioner about ways to make the treatment more comfortable. This may include distraction techniques or, if available, the use of a numbing cream.

I have been going to Amica for about 3 years now. I usually try to go to the model days, where a trainee has the opportunity to practice treatments. From first entering you are greeted by beautiful Tash, who is front of house. There is never a feeling of dread, that you are being judged or inspected to see what treatments they think you need, like you get... Show more »
I have been going to Amica for about 3 years now. I usually try to go to the model days, where a trainee has the opportunity to practice treatments.
From first entering you are greeted by beautiful Tash, who is front of house. There is never a feeling of dread, that you are being judged or inspected to see what treatments they think you need, like you get at some aesthetic places. I have definitely experienced this before myself.
You are warmly welcomed & feel at ease instantly.
I love doing the model slots. The teachers are so professional, kind & patient & the trainees are eager to learn & excited to do the various treatments, always instructed in detail & watched over by the teacher. It’s a lovely atmosphere & I always give feedback, which has always been positive & well received.
I’ve had various treatments from lip filler &
profhilo to polynucleotides & Botox. All done painlessly & with precision on a comfortable bed, which I find extremely relaxing. So much so, that I have been known to nod off a little, but I accept, I am a tad odd & could be in the minority here!
All in all, I can’t recommend Amica enough. The range of treatments is excellent & exciting & I’m never made to feel any less than anyone else because I’m not a big spender. If only!
There are so many treatments I would love to have done & this is the place I would go to have them. You should definitely give them a try. Show less »
Michela Burrows
Amica Aesthetics
7 October 2025 09:09
I have used Sarah for a couple of years now and she always understands exactly what I want, definitely not a one size fits all with her. I have had botox, booster and profhilo structura. I am constantly complimented on my skin and how fresh I look. Really can't recommend her enough. Also such a lovely lass full of banter ❤️
3 October 2025 19:07
I had an amazing experience with Janine – she’s incredibly attentive, takes the time to listen, and never rushes you. She did my Profhilo and filler treatments, and the results are fantastic! I felt completely at ease throughout, and her professional yet caring approach made all the difference. Highly recommend her! 🩷
1 October 2025 06:06
I had radio frequency micro needling approximately 12 months ago and I was very pleased with the results. Since then I've been having polynucleotides, profhilo and Botox with Janine. My skin has never looked or felt so good! I feel like it's taken "years off". Thank you so much!
28 September 2025 16:04
I had profhilo skin booster treatment at Derma Plus and I couldn't be happier with the results! I was hoping to improve my skin tone and fine lines and in just 2 days my skin is glowing. It feels amazing even when I apply makeup. Megan was professional, and very knowledgable, she answered all my questions and put me at ease throughout. The treatment room was... Show more »
I had profhilo skin booster treatment at Derma Plus and I couldn't be happier with the results! I was hoping to improve my skin tone and fine lines and in just 2 days my skin is glowing. It feels amazing even when I apply makeup. Megan was professional, and very knowledgable, she answered all my questions and put me at ease throughout.
The treatment room was immaculate and clean, and very calming. Everything about the experience was perfect. I can’t recommend Derma Plus - Sheffield and Megan highly enough Show less »
27 September 2025 09:09
I visited Julia for my Profhilo treatment and wow, my skin hasn't looked or felt bette!
Julia is just so lovely and welcoming and I felt totally safe in her hands. She was so friendly whilst also very professional. Have noticed a real difference in my skin and honestly can't wait to return for my next treatment.
Couldn't recommend her enough. Thank you! Xx
Katie Macdonald
West Park Aesthetics
24 September 2025 20:08
I visited the Tweakment Clinic this morning for my first Profhilo treatment and had a wonderful experience. I have never had any aesthetic treatments before so I was very nervous but the practitioner made me feel very comfortable and at ease and already my dull skin looks like it’s glowing, so I am very impressed! I am looking forward to the final results an... Show more »
I visited the Tweakment Clinic this morning for my first Profhilo treatment and had a wonderful experience. I have never had any aesthetic treatments before so I was very nervous but the practitioner made me feel very comfortable and at ease and already my dull skin looks like it’s glowing, so I am very impressed! I am looking forward to the final results and can’t wait to return in 3 weeks for my second course of Profhilo. Thank you for taking care of me :-) Show less »
23 September 2025 14:02
I had a full face, arms, and back peel along with two sessions of Profhilo for my face and chin filler. The results are truly amazing! Thank you so much, Dr. Ankita Mishra, for skillfully performing all these procedures with such care and expertise. I’m extremely happy with the outcome and highly recommend her!
Sania Francis
Epiderm Aesthetics
18 September 2025 09:09
“There are countless beauty clinics in London, but none match Dr. Mohan's expertise and professionalism.” He has an exceptional understanding of Botox, PROFHILO, and much more.” I previously had my Botox done in Germany, where I also manage a business and continue my thyroid hormone replacement treatment.” However, no one administers Botox in my face like D... Show more »
“There are countless beauty clinics in London, but none match Dr. Mohan's expertise and professionalism.”
He has an exceptional understanding of Botox, PROFHILO, and much more.”

I previously had my Botox done in Germany, where I also manage a business and continue my thyroid hormone replacement treatment.”
However, no one administers Botox in my face like Dr. Mohan does; the results are unparalleled.”
I never need to return for touch-ups because he knows exactly where to inject the Botox on my face.”
And the Botox looks natural—not overdone—and leaves my face fresh and rejuvenated for 4 months.”
As I am over 60 years old, I appreciate that the bruising is minimal and fades within just a few days”.

Thank you, Dr. Mohan, for your kindness and professionalism.”
You truly are the best in London's bustling beauty industry.”

Kind regards
M-Berge.” Show less »
14 September 2025 13:01
Very happy with my procedure at Intentions Clinic with Gail. I had the Profhilo structure treatment. Second application done. You can see a massive difference. Very very happy 😊 👍😁
7 September 2025 20:08
Visited Prestige for my first Profhilo treatment and Ellie was brilliant. She explained everything to me and put me immediately at ease. The whole process was great and I can't wait to go back ☺️ 10/10 thank you
6 September 2025 15:03
Went to Kim for Profhilo and Lumi Eyes. Really pleased with the results, and couldn’t ask for a lovelier lady than Kim to perform the service! Will definitely be a regular customer from now on.
Also, prices are very reasonable.
6 September 2025 08:08

Does Profhilo hurt?

Profhilo generally causes only minor discomfort during the treatment, which most people do not find unbearable. The sensation is often described as a slight tingling or prickling, which quickly subsides after the injections. Thanks to the fine needles and distraction techniques, the procedure is well tolerated.

Curious about Profhilo or want to book a treatment? Compare clinics on Injectablesbooking.co.uk, read reviews from other clients, and find the best prices and practitioners near you.

With Profhilo, you get an effective and quick way to improve your skin’s health without needing an invasive procedure.

Frequently asked questions about Profhilo treatment

Is a Profhilo treatment painful?

What do you see after Profhilo?

What are you not allowed to do after Profhilo?

Can Profhilo fail?

Why not Profhilo in forehead?

How long should bumps remain after Profhilo?

What is better, Profhilo or Botox?

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