Rejuran Under Eyes

12 August 2026
Tom van Eijk
The contents of this article is medically checked by: Drs. Tom van Eijk

Rejuran under the eyes is an injectable treatment containing polynucleotides, usually shortened to PN. Around the eyes, it is mainly considered when the treatment goal is to improve the quality of thin skin, fine lines or a finely creased, crepey texture.

It is not primarily intended to fill a deep tear trough with volume. A hollow under the eyes, pigmentation, visible blood vessels and prominent eye bags can have different causes and require a different assessment.

Rejuran is a brand rather than the name of the treatment category. Within the range, Rejuran I is positioned for thinner, delicate skin, including fine lines around the eye area. Rejuran products contain salmon-derived polynucleotides.

Whether treatment is relevant therefore depends more on why the under-eye area looks the way it does than on the Rejuran name itself.

For the broader treatment context, see the main Rejuran guide.

Rejuran Under Eyes

When might Rejuran under the eyes be considered?

Rejuran under the eyes is mainly discussed when skin quality is the primary concern. This can include superficial fine lines, thin-looking skin and a finely wrinkled or crepey texture.

A practitioner should first assess which factors are actually contributing to the appearance of the area.

Fine lines and thin under-eye skin

Polynucleotide treatment may be considered where superficial lines or thin, crepey skin are the main concern. The aim is a gradual change in skin quality rather than an obvious increase in volume.

The dedicated Rejuran for fine lines guide covers this overlap in more detail.

Dark circles

Dark circles are not one single condition. Their appearance can be influenced by pigmentation, visible blood vessels, thin skin, anatomical shadowing, swelling or a combination of factors.

This means that describing Rejuran simply as a treatment “for dark circles” is too broad. It may be discussed where skin quality contributes to the appearance, but another approach may be more relevant when the underlying cause is different.

For the concern-specific explanation, see Rejuran for dark circles.

Deep hollows or prominent eye bags

A pronounced tear trough does not result from skin quality alone. Facial anatomy and the distribution of volume beneath the eye can contribute to the shadow.

Rejuran is not primarily designed to replace that missing volume.

Prominent lower-eyelid bags can also have different underlying causes, including swelling and the position of fat beneath the eye. These require assessment before an injectable treatment is chosen.

What can Rejuran under the eyes not correct?

Rejuran is not a general solution for every under-eye hollow, dark circle or eye bag.

It is not primarily intended to:

  • replace significant lost volume;

  • fill a pronounced tear trough;

  • directly remove skin pigmentation;

  • directly remove visible blood vessels;

  • remove prominent structural eye bags;

  • correct every cause of under-eye shadowing.

If anatomy, volume loss, pigmentation, vascular visibility or swelling is the dominant issue, another treatment direction — or no cosmetic treatment — may be more appropriate.

The distinction is particularly important when comparing Rejuran with a volumising injectable. See Rejuran vs fillers for the dedicated comparison.

Is salmon DNA good for the skin around the eyes?

Purified salmon-derived polynucleotides are used in cosmetic injectable treatments around the eyes. Research into PN injections as a treatment category has reported possible improvements in aspects of fine lines and skin quality, but the evidence remains limited.

Importantly, research into one PN product cannot automatically be used as proof that Rejuran will produce the same result.

What should be assessed before Rejuran under the eyes?

  1. 1 Identify the main under-eye concern
  2. 2 Assess skin quality and fine lines
  3. 3 Check for hollows, bags or shadowing
  4. 4 Discuss pigmentation and vascular visibility
  5. 5 Confirm which Rejuran product will be used
  6. 6 Agree realistic goals and limitations

What results can you expect from Rejuran under the eyes?

Rejuran under the eyes is intended to produce gradual changes in skin quality, rather than the immediate volume effect associated with a traditional filler.

Where fine lines or a thin, finely creased under-eye texture are the main concern, treatment may result in a visible improvement. How much difference is noticeable and when it appears varies between individuals.

The outcome can depend on:

  • the starting condition of the skin;

  • the exact under-eye concern;

  • the Rejuran product used;

  • the treatment plan;

  • individual response.

If deep hollowing, pigmentation or prominent eye bags are mainly responsible for the appearance, Rejuran may produce little visible change in that specific concern.

A practitioner should explain what they expect the treatment to change and what is likely to remain before treatment begins.

Rejuran before and after photos

Rejuran picture of Oran Aesthetics (before)
Rejuran picture of Oran Aesthetics (after)
These pictures are from Oran Aesthetics
Rejuran picture of SkinSurgery Clinics Bergschenhoek (before)
Rejuran picture of SkinSurgery Clinics Bergschenhoek (after)
These pictures are from SkinSurgery Clinics Bergschenhoek

Rejuran under-eye side effects and recovery

What can the under-eye area look like after treatment?

What should you do after treatment?

When should you contact the clinic?

What should you tell the practitioner beforehand?

What does Rejuran under the eyes cost in the UK?

The price of Rejuran under-eye treatment can vary according to the clinic, product used, proposed treatment plan and number of sessions.

Rather than comparing only a single advertised starting price, check what the complete proposed treatment course includes.

Useful questions include:

  • Which Rejuran formulation will be used?

  • How much product is proposed?

  • How many sessions are being recommended?

  • Are consultation and review appointments included?

  • What follow-up is available if you have concerns?

For current price information and the factors behind price differences, see Rejuran costs.

How do you compare clinics for Rejuran under the eyes?

For an injectable treatment around the eyes, compare more than price. The consultation should establish who will perform the treatment, what product will be used, what is causing the concern and why Rejuran is being proposed.

Useful points to compare include:

  • who will actually perform the injections;

  • the practitioner's relevant professional background;

  • professional registration where relevant to their role;

  • experience with injectable treatments around the eyes;

  • experience using Rejuran or comparable PN treatments;

  • which Rejuran formulation will be used;

  • why that product is being proposed;

  • whether alternatives or no treatment are discussed;

  • how realistic results and limitations are explained;

  • how the clinic manages follow-up and unexpected reactions;

  • the cost of the complete proposed treatment plan.

Professional registration can provide useful information about a practitioner's professional status where applicable, but registration alone does not demonstrate extensive experience with Rejuran or the under-eye area.

For a more detailed comparison checklist, read how to choose a Rejuran practitioner.

You can then decide whether you want to request a consultation. Choosing not to proceed remains a valid option.

Compare clinics in United Kingdom

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Hampstead Aesthetics
Hampstead Aesthetics
London, West End Lane 269
Rejuran from
£ 295,00
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Simply Clinics
Simply Clinics
Uxbridge, High Street 18
Rejuran from
£ 290,00
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The Refining Room
The Refining Room
Menai Bridge, St George's Road
Rejuran from
£ 230,00
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Skinmedika® Chester
Skinmedika® Chester
Chester, Bridge Street 27
Rejuran from
£ 180,00
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Aesculus Clinic
Aesculus Clinic
New Malden, High Street 157
Rejuran from
£ 300,00
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Aestha Clinic
Aestha Clinic
London, Welbeck Street 21
Rejuran from
£ 350,00
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InnoDerm Clinic
InnoDerm Clinic
London, Judd Street 108-110
Rejuran from
£ 250,00
View profile

Rejuran clinic reviews

I had a really great experience at Aestha Clinic. Zainub at reception was so friendly and helped calm my nerves straight away as I was a bit worried about rejuran healer since it’s known to be really painful and this was a new clinic for me. Jessica, the aesthetic nurse was amazing, very knowledgeable and honest. She recommended what would actually benefit m... Show more »
I had a really great experience at Aestha Clinic. Zainub at reception was so friendly and helped calm my nerves straight away as I was a bit worried about rejuran healer since it’s known to be really painful and this was a new clinic for me. Jessica, the aesthetic nurse was amazing, very knowledgeable and honest. She recommended what would actually benefit my skin and advised against anything unnecessary, which made me feel like she genuinely had my best interests at heart. She even created a treatment plan for me and recommended skincare products that would work best for my skin concerns. The Rejuran injections were about a 4–5/10 pain, small pricks with some mild to moderate discomfort as the product is being injected, but definitely tolerable. She was also very quick and efficient, which made the whole process much easier and definitely helped reduce the pain. Would highly, highly recommend and I have already booked my next session at Aestha. Show less »
Khusa Gurung
Aestha Clinic
27 March 2026 08:08

Frequently asked questions about Rejuran under the eyes

What is Rejuran under-eye treatment?

Is salmon DNA good for the under-eye area?

What is Rejuran I?

Can Rejuran help dark circles?

Is Rejuran the same as under-eye filler?

Can Rejuran fill a tear trough?

Can Rejuran remove eye bags?

What are the side effects of Rejuran under the eyes?

How many Rejuran under-eye treatments are needed?

When can you see results from Rejuran under the eyes?

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