Rejuran polynucleotides

Rejuran polynucleotides are purified DNA fragments used in injectable skin-quality treatments. They are discussed in aesthetic medicine for their role in supporting skin texture, skin repair and overall skin quality.

Unlike dermal fillers, Rejuran is not designed to add obvious volume or change facial contours. Its focus is more on supporting the skin itself, including fine lines, texture, elasticity and delicate-looking skin.

Rejuran is the treatment or product line. Polynucleotides are the active ingredients used in the treatment. This is why the terms are often used together, even though they do not mean exactly the same thing.

Read more about the general Rejuran treatment if you want a broader introduction before looking at polynucleotides in detail.

What are polynucleotides?

Polynucleotides are chains of nucleotides, the building blocks of DNA. In aesthetic treatments, they are used because of their possible role in supporting skin repair, skin renewal and the extracellular matrix.

In purified form, polynucleotides are used in regenerative skin-quality treatments. They are often discussed in relation to:

• skin repair;

• skin texture;

• collagen support;

• elasticity;

• skin-barrier support;

• fine lines;

• overall skin quality.

Polynucleotides are not designed to create filler-like volume. The aim is to support skin condition and skin quality rather than to reshape the face.

What is the difference between Rejuran and polynucleotides?

Rejuran is the treatment or product name. Polynucleotides are the active ingredients used within the treatment.

A simple way to understand it is that Rejuran is the product line, while polynucleotides are the ingredient category.

The confusion happens because some clinics talk about a Rejuran treatment, while others describe a polynucleotide treatment. In practice, both terms often refer to similar regenerative injectable skin-quality treatments, but the exact product and protocol can vary by clinic.

What is the difference between PN and PDRN?

PN and PDRN are both DNA-derived ingredients, but they differ in structure, fragment length and how they are described in aesthetic medicine.

For most users, the key point is that Rejuran is known for using polynucleotides as a regenerative skin-quality technology. A practitioner can explain which product is being used and why it suits your skin.

What are Rejuran polynucleotides used for?

Rejuran polynucleotides are mainly considered when skin quality is the main concern.

They may be discussed for:

• fine lines;

• thin or delicate-looking skin;

• reduced elasticity;

• dull skin;

• uneven texture;

• superficial acne scarring;

• skin ageing;

• under-eye skin quality.

For more specific information, read about Rejuran for fine lines, Rejuran for acne scars and Rejuran under eyes.

Rejuran product variants

Within the Rejuran product line, different variants may be used for different skin concerns.

The choice of product depends on the treatment area, skin concern, medical suitability and practitioner assessment.

Rejuran polynucleotides and visible skin results

Before-and-after photos may help show the type of skin-quality changes people look for with Rejuran, such as smoother texture, softer-looking fine lines or improved overall skin appearance.

Photos should be viewed carefully. Results vary by person and depend on skin condition, treatment area, number of sessions, product choice, practitioner technique and aftercare.

Rejuran polynucleotides vs other injectables

Rejuran vs Profhilo

Read more on Rejuran vs Profhilo.

Polynucleotides vs fillers

Read more on Rejuran vs fillers.

Polynucleotides vs skin boosters

Many skin boosters use hyaluronic acid and focus mainly on hydration. Polynucleotides are more focused on regenerative skin-quality support and texture.

Read more on Rejuran vs skin boosters.

Are Rejuran polynucleotides safe?

Rejuran polynucleotides are used in aesthetic clinics, but they are not suitable for everyone. A consultation is needed to assess your skin, medical history, allergies, current medication and expectations.

Temporary side effects may include:

• redness;

• swelling;

• small bumps;

• bruising;

• tenderness;

• visible injection marks.

Treatment may be postponed or avoided during pregnancy or breastfeeding, with active skin infections, certain allergies or some medical conditions. Always follow the advice of your practitioner.

Read more about Rejuran side effects for a fuller explanation of possible risks.

Compare Rejuran clinics

If you want to know whether Rejuran polynucleotides suit your skin goals, compare clinics and practitioners carefully. Look beyond price and check experience, consultation quality, treatment explanation and aftercare.

Useful pages to read next include:

• Rejuran treatment

• Rejuran cost

• Rejuran reviews

• Rejuran before and after

This gives you a clearer view of the treatment, possible results and available UK clinics.

Frequently asked questions about Rejuran polynucleotides