Rejuran for Fine Lines

Q: Does Rejuran help with fine lines?

Rejuran may help soften the appearance of subtle fine lines by supporting skin quality, texture and collagen-related repair processes. Results vary per person.

Q: Can Rejuran be used under the eyes?

Rejuran may be considered for subtle under-eye lines, but this area requires careful assessment by an appropriately trained practitioner.

Q: How many Rejuran treatments are needed for fine lines?

Many clinics recommend a course of treatments, but the number of sessions depends on your skin, treatment area and practitioner’s advice.

Q: How long does it take to see results?

Rejuran results usually develop gradually over several weeks. The timeline can vary depending on skin condition and treatment plan.

Q: Are there side effects or downtime?

Temporary redness, swelling, bruising, tenderness or small injection bumps can occur. Recovery varies per person.

Q: Does Rejuran treatment hurt?

You may feel small pinpricks during treatment. Some clinics use numbing cream to make the treatment more comfortable.

Q: What is better for fine lines: Rejuran, Botox or fillers?

It depends on the cause of the lines. Rejuran targets skin quality, botulinum toxin targets dynamic movement lines and fillers are usually used for volume loss.

Q: How much does Rejuran for fine lines cost?

The cost depends on the clinic, treatment area, number of sessions and product used. Ask the clinic for a personalised quote during consultation.

The contents of this article is medically checked by:
Drs. Tom van Eijk

Rejuran for fine lines is an injectable skin-quality treatment that may help soften the appearance of subtle lines and improve skin texture over time.

The treatment uses polynucleotides, which are used in aesthetic medicine to support processes involved in skin repair, collagen production and skin resilience. Rejuran is often considered for early fine lines, thin-looking skin, crepey texture or subtle lines under the eyes.

Rejuran is not a filler and does not add volume. Its role is more focused on supporting skin quality, firmness and gradual improvement in texture.

What causes fine lines?

Fine lines can develop when collagen and elastin levels change, the skin becomes thinner and the skin’s natural repair processes slow down.

Common contributing factors include:

Sun exposure
Smoking
Stress
Natural ageing
Skin dryness
Repeated facial movement
Loss of skin elasticity

Rejuran is used as a skin-quality treatment for early visible signs of ageing, especially when the concern is texture, thin skin or subtle lines rather than deep wrinkles or volume loss.

How does Rejuran work for fine lines?

Rejuran contains polynucleotides, which are used to support skin repair and regenerative skin-quality processes.

In aesthetic treatments, polynucleotides are discussed for their role in supporting fibroblast activity. Fibroblasts are cells in the dermis involved in producing collagen, elastin and other structural components of the skin.

By supporting these processes, Rejuran may help improve the appearance of fine lines, skin texture and firmness over time. The effect is gradual and results vary per person.

Polynucleotides and PDRN

Rejuran is commonly associated with polynucleotides and PDRN-related skin repair technology. Clinics should explain which Rejuran product is being used, why it is suitable and what results are realistic for your skin.

Collagen and elastin support

Collagen helps give the skin firmness, while elastin helps with flexibility. When these structures weaken, fine lines and crepey texture can become more visible.

Suitable treatment areas

Rejuran may be considered for fine lines in areas where the skin looks thin, delicate or uneven in texture.

Common treatment areas include:

Under the eyes
Cheeks
Around the mouth
Forehead
Neck, depending on the clinic’s assessment

The treatment area, number of sessions and injection technique should be decided during consultation.

Results and number of sessions

Rejuran results usually develop gradually. It is not designed to give the immediate smoothing effect of a filler or the muscle-relaxing effect of botulinum toxin.

Many clinics recommend a course of treatments, but the exact number of sessions depends on skin quality, line depth, treatment area and the practitioner’s advice.

Treatment	Often used for	Effect on fine lines	Recovery	Typical duration
Rejuran	Fine lines, thin-looking skin, texture	May soften subtle lines and improve skin quality	Temporary redness, swelling or small bumps may occur	Varies per person
Botulinum toxin	Dynamic expression lines	Relaxes muscle movement that contributes to lines	Usually minimal downtime	Varies per person
Fillers	Volume loss or deeper folds	Limited role for very superficial fine lines	Swelling or bruising may occur	Varies by product and area
Profhilo	Skin hydration and laxity	May improve skin quality and hydration	Temporary bumps may occur	Varies per person
Skinboosters	Hydration and glow	May improve superficial dehydration lines	Usually short recovery	Varies per person

The best option depends on whether your fine lines are mainly caused by movement, skin thinning, dehydration, texture changes or volume loss.

Recovery and possible side effects

Temporary reactions can occur after Rejuran injections. These may include:

Redness
Mild swelling
Small injection bumps
Tenderness
Bruising
Skin sensitivity

Recovery varies per person and depends on the treatment area, injection technique and skin sensitivity.

Your clinic may advise you to avoid sauna, strong sun exposure, alcohol and intense exercise for a short period after treatment. Always follow the aftercare advice given by your practitioner.

Who may be suitable for Rejuran?

Rejuran may be suitable for people with early or subtle signs of skin ageing who want to improve skin quality rather than add volume.

It may be considered for:

Early fine lines
Thin-looking or crepey skin
Dry-looking skin texture
Skin that needs collagen support
Uneven texture
Mild loss of firmness

Rejuran may be less suitable if the main concern is deep folds, significant volume loss or strong dynamic wrinkles. In those cases, a practitioner may discuss alternatives such as fillers, botulinum toxin or other skin-quality treatments.

Suitability should always be assessed during consultation.

Rejuran vs other treatments for fine lines

Different injectable treatments work in different ways. Rejuran is mainly focused on skin quality and texture, while other treatments may target movement, volume or hydration.

Botulinum toxin may be considered for dynamic lines caused by repeated facial movement.
Fillers may be more relevant when fine lines are linked to volume loss or deeper folds.
Profhilo is usually used for hydration and skin bio-remodelling.
Skinboosters are often used to improve hydration and superficial skin quality.

Rejuran may be considered when fine lines are linked to thin skin, texture changes or reduced firmness.

Compare Rejuran clinics

Before booking Rejuran for fine lines, compare clinics carefully.

Look at practitioner experience, consultation quality, treatment information, reviews, aftercare guidance and how clearly the clinic explains possible side effects and expected results.

Ask which practitioner will carry out the treatment, what product will be used and whether Rejuran is suitable for your skin concern.