How Long Does Rejuran Last
Drs. Tom van Eijk
"How long do Rejuran results last?" is a common question among those considering polynucleotide injections for skin rejuvenation. The effects build gradually and vary per person, depending on skin type, age, the number of sessions, and your treatment plan.
In this guide, we provide a clear timeline, explain the factors that influence how long results may remain visible, and share practical tips for aftercare and maintenance.
What Influences the Duration of Rejuran Results?
For those who complete the full treatment protocol and maintain a healthy lifestyle, results may remain visible for 6 to 12 months on average.
Key factors include:
Age: Younger skin generally retains results for a longer period.
Skin type: Dry or thin skin may lose firmness more quickly.
Lifestyle: Smoking, excessive sun exposure, and poor hydration can reduce how long the effects last.
Number of sessions: A course of 2 to 4 sessions is usually recommended for optimal outcomes.
Maintenance: Regular touch-up sessions can help prolong the visible effects.
Note: The duration of Rejuran results varies. Suitability and a tailored treatment plan should be assessed during your consultation.
Result timeline: When will you notice changes?
Timeframe | Expected Visible Effects | Quick Advice |
Week 1–2 | Initial skin improvements, such as hydration and smoothness. | Follow standard aftercare advice. |
Week 3–4 | May improve the appearance of skin texture and fine lines. | Keep the skin hydrated and protected. |
Month 2–3 | Firmness and elasticity often increase as collagen production is supported. | Attend a follow-up assessment with your practitioner. |
Month 6–12 | Effects will gradually begin to fade. | Consider booking a maintenance session. |
Tip: Individual results vary. Discuss with your aesthetic practitioner which schedule is best suited for your skin.
Treatment Overview
Rejuran is a polynucleotide injection designed to support the skin from within by encouraging collagen production and stimulating the extracellular matrix (ECM).
Duration per session: 30 to 45 minutes
Number of sessions: 2 to 4, depending on individual skin condition
Mechanism: Supports the ECM and may improve skin texture without adding volume
Why can Rejuran sometimes feel uncomfortable? Minor injections are used, and temporary sensitivity is normal. Any discomfort usually settles quickly.
Read more about the Rejuran treatment process
Possible Side Effects & Safety
While Rejuran is a common treatment, there are potential side effects to be aware of:
Mild redness, swelling, or small bumps at the injection sites
Temporary discomfort during or immediately after the treatment
Occasional, mild bruising
Precaution: Avoid extreme heat, saunas, or intense exercise for 24 to 48 hours following the procedure.
Tip: The most common side effects, such as mild redness or swelling, usually settle within a few days. Always consult your clinic if you have concerns.
Read more about Rejuran side effects
Aftercare Advice
Proper aftercare can support the healing process and the longevity of your results:
Keep the skin well hydrated.
Avoid direct sunlight and sunbeds; use a high-SPF sunscreen.
Refrain from strenuous sports or sauna use for 24 to 48 hours post-treatment.
Consult your doctor or nurse prescriber if side effects persist.
Read everything about Rejuran recovery
Maintenance and Future Sessions
Complete the full initial treatment protocol to achieve the best possible outcome.
Maintenance sessions are typically considered after 6 to 12 months, depending on how your skin responds.
Discuss with your practitioner how often a touch-up is necessary for your specific skin type and goals.
Related Treatments
If you are looking for treatments tailored to specific concerns such as scars, dark circles, or fine lines, explore our related Rejuran pages. Compare Rejuran with dermal fillers or Skinboosters
"Would you like to find a clinic that offers excellent aftercare? Compare Rejuran clinics in your area and schedule a consultation today."
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Frequently asked questions about Rejuran Duration
When will I start to see results from Rejuran?
Early improvements in hydration and texture are often visible within 1 to 2 weeks. Optimal results are usually seen after completing a course of 2 to 4 sessions.
How many Rejuran sessions will I need?
Most people require 2 to 4 sessions, depending on their individual skin condition and aesthetic goals. Suitability should be assessed during a consultation.
How long do side effects last?
Mild redness, swelling, or small bumps at the injection sites are common and typically settle within 1 to 3 days.
Can Rejuran help with acne scars?
Yes, Rejuran S is specifically designed to support collagen production, which may improve the appearance of scars. Always discuss this with a qualified practitioner.
What are the limitations of the treatment?
The main limitations include temporary post-treatment side effects and the fact that results are not permanent; the effects gradually fade over 6 to 12 months, depending on lifestyle and skin type.
Does age affect how long Rejuran lasts?
Yes. Younger skin often retains results for a longer period, while older or more mature skin may require maintenance sessions slightly sooner to sustain the effects.
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